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Selected Module: B_1_2


Module Info

Module_Name B_1_2
Cell_Type B
Name B_1_2: endoplasmic reticulum protein-containing complex
Meta_Module B_2
Gene_Number 27

Genes:

CRELD2, DNAJB11, DNAJC3, EDEM2, FKBP11, HDLBP, HSP90B1, HSPA5, LMAN1, LMAN2, MYDGF, MZB1, PDIA4, PDIA6, PPIB, PRDX4, RABAC1, SEC11C, SELENOK, SELENOS, SPCS1, SPCS2, SPCS3, SSR3, TMED10, TMED9, TRAM1


UMAP Visualizations


UMAP for B_1_2

UMAP for B_1_2


Word Cloud

Enriched TF

Wordcloud for B_1_2
TF p.adjust Genes
USF 0.00826796953778515 FKBP11/PRDX4/SEC11C/TMED10
PGM3 0.00826796953778515 HDLBP/MYDGF/PPIB/RABAC1


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_1_2 GO:0072594 establishment of protein localization to organelle 7/25 462/18986 1.58737356448817e-06 7.38128707486998e-05 5.33023333759711e-05 HSPA5/LMAN1/SPCS1/SPCS2/SPCS3/SSR3/TRAM1 7
GO B_1_2 GO:0035966 response to topologically incorrect protein 5/25 160/18986 1.85087004719622e-06 7.82413247223855e-05 5.65002435459898e-05 DNAJC3/EDEM2/HSPA5/SELENOS/TRAM1 5
reactome B_1_2 R-HSA-381038 XBP1(S) activates chaperone genes 4/21 50/11146 2.02728327516868e-06 1.45964395812145e-05 9.17612429813193e-06 DNAJB11/DNAJC3/MYDGF/PDIA6 4
GO B_1_2 GO:0003756 protein disulfide isomerase activity 3/27 19/18737 2.54619508387113e-06 3.8192926258067e-05 2.01015401358247e-05 CRELD2/PDIA4/PDIA6 3
GO B_1_2 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 3/27 19/18737 2.54619508387113e-06 3.8192926258067e-05 2.01015401358247e-05 CRELD2/PDIA4/PDIA6 3
GO B_1_2 GO:0061077 chaperone-mediated protein folding 4/25 76/18986 2.81338828713072e-06 0.00010901879612631 7.87255143504122e-05 FKBP11/HSPA5/PDIA4/PPIB 4
MeSH_gene2pubmed B_1_2 D015700 HIV Envelope Protein gp41 5/27 230/26076 3.52203895863826e-06 0.00021391752411939 0.00016039423955682 HSPA5/LMAN1/PDIA4/PDIA6/RABAC1 5
GO B_1_2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane 4/27 81/19960 4.11349759522156e-06 2.8337427878193e-05 1.010332742686e-05 LMAN1/LMAN2/TMED10/TMED9 4
MeSH_gene2pubmed B_1_2 D005990 Glycerol 5/27 239/26076 4.24724645856357e-06 0.00024506612065911 0.00018374929415469 DNAJB11/HSP90B1/HSPA5/PDIA4/PPIB 5
GO B_1_2 GO:0016853 isomerase activity 5/27 180/18737 5.263389175619e-06 6.3160670107428e-05 3.32424579512779e-05 CRELD2/FKBP11/PDIA4/PDIA6/PPIB 5