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Selected Module: B_1_2
Module Info
| Module_Name | B_1_2 |
| Cell_Type | B |
| Name | B_1_2: endoplasmic reticulum protein-containing complex |
| Meta_Module | B_2 |
| Gene_Number | 27 |
Genes:
CRELD2, DNAJB11, DNAJC3, EDEM2, FKBP11, HDLBP, HSP90B1, HSPA5, LMAN1, LMAN2, MYDGF, MZB1, PDIA4, PDIA6, PPIB, PRDX4, RABAC1, SEC11C, SELENOK, SELENOS, SPCS1, SPCS2, SPCS3, SSR3, TMED10, TMED9, TRAM1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| USF | 0.00826796953778515 | FKBP11/PRDX4/SEC11C/TMED10 |
| PGM3 | 0.00826796953778515 | HDLBP/MYDGF/PPIB/RABAC1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_1_2 | GO:0030133 | transport vesicle | 4/27 | 453/19960 | 0.00303709665864521 | 0.00991052593873701 | 0.00353346425659554 | LMAN1/RABAC1/TMED10/TMED9 | 4 |
| GO | B_1_2 | GO:0012507 | ER to Golgi transport vesicle membrane | 2/27 | 64/19960 | 0.00337349091258327 | 0.0104578218290081 | 0.00372859521917098 | LMAN1/TMED10 | 2 |
| GO | B_1_2 | GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 2/25 | 66/18986 | 0.00339093602622201 | 0.0375425060046008 | 0.0271104910367123 | SELENOK/SELENOS | 2 |
| GO | B_1_2 | GO:0019905 | syntaxin binding | 2/27 | 61/18737 | 0.00347259545004809 | 0.0148825519287775 | 0.00783292206777765 | TMED10/TMED9 | 2 |
| GO | B_1_2 | GO:0006903 | vesicle targeting | 2/25 | 67/18986 | 0.00349246070001994 | 0.037767307569983 | 0.0272728265191275 | TMED10/TMED9 | 2 |
| WikiPathways | B_1_2 | WP28 | Selenium metabolism and selenoproteins | 2/20 | 47/8836 | 0.00495030913000526 | 0.0191824478787704 | 0.0130271292894875 | SELENOK/SELENOS | 2 |
| GO | B_1_2 | GO:0048029 | monosaccharide binding | 2/27 | 74/18737 | 0.00506671653445602 | 0.0195034652169049 | 0.0102649816931078 | LMAN1/LMAN2 | 2 |
| GO | B_1_2 | GO:0044183 | protein folding chaperone | 2/27 | 75/18737 | 0.0052009240578413 | 0.0195034652169049 | 0.0102649816931078 | HSP90B1/HSPA5 | 2 |
| GO | B_1_2 | GO:0016209 | antioxidant activity | 2/27 | 86/18737 | 0.00678386683441134 | 0.0239430594155694 | 0.0126016102187208 | PRDX4/SELENOS | 2 |
| GO | B_1_2 | GO:0005798 | Golgi-associated vesicle | 2/27 | 95/19960 | 0.00728151891231058 | 0.0214978177411074 | 0.00766475674980061 | TMED10/TMED9 | 2 |