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Selected Module: B_1_2


Module Info

Module_Name B_1_2
Cell_Type B
Name B_1_2: endoplasmic reticulum protein-containing complex
Meta_Module B_2
Gene_Number 27

Genes:

CRELD2, DNAJB11, DNAJC3, EDEM2, FKBP11, HDLBP, HSP90B1, HSPA5, LMAN1, LMAN2, MYDGF, MZB1, PDIA4, PDIA6, PPIB, PRDX4, RABAC1, SEC11C, SELENOK, SELENOS, SPCS1, SPCS2, SPCS3, SSR3, TMED10, TMED9, TRAM1


UMAP Visualizations


UMAP for B_1_2

UMAP for B_1_2


Word Cloud

Enriched TF

Wordcloud for B_1_2
TF p.adjust Genes
USF 0.00826796953778515 FKBP11/PRDX4/SEC11C/TMED10
PGM3 0.00826796953778515 HDLBP/MYDGF/PPIB/RABAC1


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_1_2 GO:0015036 disulfide oxidoreductase activity 2/27 40/18737 0.00150794846607433 0.00822517345131455 0.00432903865858661 PDIA4/PDIA6 2
GO B_1_2 GO:0140662 ATP-dependent protein folding chaperone 2/27 40/18737 0.00150794846607433 0.00822517345131455 0.00432903865858661 HSP90B1/HSPA5 2
reactome B_1_2 R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 3/21 125/11146 0.00158000978483258 0.00517094111399752 0.003250737834823 DNAJC3/HSP90B1/PDIA6 3
MeSH_gene2pubmed B_1_2 D009439 Neuraminidase 3/27 225/26076 0.00159119842008413 0.0311227623182558 0.0233356842338833 HDLBP/HSP90B1/LMAN1 3
MeSH_gene2pubmed B_1_2 D053299 Apolipoprotein B-100 2/27 58/26076 0.00164670552992848 0.0316716363589578 0.0237472271158107 HSP90B1/HSPA5 2
GO B_1_2 GO:0016859 cis-trans isomerase activity 2/27 42/18737 0.00166159107596305 0.00830795537981525 0.00437260809463961 FKBP11/PPIB 2
GO B_1_2 GO:1903573 negative regulation of response to endoplasmic reticulum stress 2/25 46/18986 0.0016627525236109 0.0203468400915544 0.0146930209150104 HSPA5/SELENOS 2
MeSH_gene2pubmed B_1_2 D053454 Caspase 12 2/27 59/26076 0.00170339831022421 0.0322249450819466 0.0241620950992977 HSP90B1/HSPA5 2
GO B_1_2 GO:0006984 ER-nucleus signaling pathway 2/25 48/18986 0.00180924120326158 0.0215717220388881 0.0155775423438716 HSPA5/SELENOS 2
MeSH_gene2pubmed B_1_2 D019163 Reducing Agents 2/27 61/26076 0.0018195481817188 0.0338062524334156 0.025347751072031 HDLBP/TMED10 2