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Selected Module: B_1_2


Module Info

Module_Name B_1_2
Cell_Type B
Name B_1_2: endoplasmic reticulum protein-containing complex
Meta_Module B_2
Gene_Number 27

Genes:

CRELD2, DNAJB11, DNAJC3, EDEM2, FKBP11, HDLBP, HSP90B1, HSPA5, LMAN1, LMAN2, MYDGF, MZB1, PDIA4, PDIA6, PPIB, PRDX4, RABAC1, SEC11C, SELENOK, SELENOS, SPCS1, SPCS2, SPCS3, SSR3, TMED10, TMED9, TRAM1


UMAP Visualizations


UMAP for B_1_2

UMAP for B_1_2


Word Cloud

Enriched TF

Wordcloud for B_1_2
TF p.adjust Genes
USF 0.00826796953778515 FKBP11/PRDX4/SEC11C/TMED10
PGM3 0.00826796953778515 HDLBP/MYDGF/PPIB/RABAC1


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
reactome B_1_2 R-HSA-446203 Asparagine N-linked glycosylation 5/21 306/11146 0.0002138770335468 0.00088250388117773 0.00055479045161758 EDEM2/LMAN1/LMAN2/TMED10/TMED9 5
reactome B_1_2 R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones 2/21 12/11146 0.00022062597029443 0.00088250388117773 0.00055479045161758 HSP90B1/HSPA5 2
MeSH_gene2pubmed B_1_2 D007535 Isomerases 3/27 116/26076 0.00023208757639689 0.00669970180835962 0.0050234013376554 HSP90B1/PDIA4/PDIA6 3
MeSH_gene2pubmed B_1_2 D017038 Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase 3/27 117/26076 0.00023803100012369 0.00669970180835962 0.0050234013376554 HSPA5/LMAN1/LMAN2 3
MeSH_gene2pubmed B_1_2 D054464 Peroxiredoxins 3/27 117/26076 0.00023803100012369 0.00669970180835962 0.0050234013376554 HSP90B1/PPIB/PRDX4 3
reactome B_1_2 R-HSA-204005 COPII-mediated vesicle transport 3/21 69/11146 0.00027880979124737 0.00105654236683214 0.0006642006107278 LMAN1/LMAN2/TMED10 3
GO B_1_2 GO:0016485 protein processing 4/25 246/18986 0.0002808433239299 0.00563825254761182 0.00407153947411018 SEC11C/SPCS1/SPCS2/SPCS3 4
GO B_1_2 GO:0034620 cellular response to unfolded protein 3/25 99/18986 0.00029100658310254 0.00563825254761182 0.00407153947411018 EDEM2/HSPA5/SELENOS 3
reactome B_1_2 R-HSA-948021 Transport to the Golgi and subsequent modification 4/21 186/11146 0.0003597831654901 0.00129521939576438 0.00081424611137234 LMAN1/LMAN2/TMED10/TMED9 4
MeSH_gene2pubmed B_1_2 D013954 D013954 3/27 137/26076 0.00037835413735833 0.0103011474872607 0.0077237464512709 HSP90B1/HSPA5/PDIA4 3