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Selected Module: B_1_2


Module Info

Module_Name B_1_2
Cell_Type B
Name B_1_2: endoplasmic reticulum protein-containing complex
Meta_Module B_2
Gene_Number 27

Genes:

CRELD2, DNAJB11, DNAJC3, EDEM2, FKBP11, HDLBP, HSP90B1, HSPA5, LMAN1, LMAN2, MYDGF, MZB1, PDIA4, PDIA6, PPIB, PRDX4, RABAC1, SEC11C, SELENOK, SELENOS, SPCS1, SPCS2, SPCS3, SSR3, TMED10, TMED9, TRAM1


UMAP Visualizations


UMAP for B_1_2

UMAP for B_1_2


Word Cloud

Enriched TF

Wordcloud for B_1_2
TF p.adjust Genes
USF 0.00826796953778515 FKBP11/PRDX4/SEC11C/TMED10
PGM3 0.00826796953778515 HDLBP/MYDGF/PPIB/RABAC1


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_1_2 GO:0140534 endoplasmic reticulum protein-containing complex 11/27 116/19960 1.89513781177115e-18 1.17498544329811e-16 4.1892520049678e-17 DNAJB11/HSP90B1/HSPA5/MZB1/PDIA6/PPIB/SEC11C/SELENOS/SPCS1/SPCS2/SPCS3 11
KEGG B_1_2 hsa04141 Protein processing in endoplasmic reticulum 12/17 170/8541 1.4865935043275e-17 2.82452765822225e-16 2.50373642834105e-16 DNAJB11/DNAJC3/EDEM2/HSP90B1/HSPA5/LMAN1/LMAN2/PDIA4/PDIA6/SELENOS/SSR3/TRAM1 12
GO B_1_2 GO:0034663 endoplasmic reticulum chaperone complex 6/27 11/19960 1.55125867831475e-15 4.80890190277574e-14 1.71454906550578e-14 DNAJB11/HSP90B1/HSPA5/MZB1/PDIA6/PPIB 6
GO B_1_2 GO:0006457 protein folding 10/25 231/18986 1.62963951868128e-13 7.57782376186795e-11 5.47215796272977e-11 DNAJB11/DNAJC3/FKBP11/HSP90B1/HSPA5/LMAN1/PDIA4/PDIA6/PPIB/PRDX4 10
GO B_1_2 GO:0005788 endoplasmic reticulum lumen 10/27 314/19960 5.35814349695008e-12 1.10734965603635e-10 3.9481057345948e-11 DNAJB11/DNAJC3/EDEM2/HSP90B1/HSPA5/MYDGF/MZB1/PDIA4/PDIA6/PPIB 10
MeSH_gene2pubmed B_1_2 D037281 Calnexin 8/27 201/26076 2.12201956605786e-11 2.44881057923077e-08 1.83610535084164e-08 DNAJB11/HSP90B1/HSPA5/LMAN1/LMAN2/PDIA4/PPIB/TMED9 8
GO B_1_2 GO:0045047 protein targeting to ER 6/25 46/18986 2.46584115501058e-11 5.7330806853996e-09 4.14001751814935e-09 HSPA5/SPCS1/SPCS2/SPCS3/SSR3/TRAM1 6
GO B_1_2 GO:0072599 establishment of protein localization to endoplasmic reticulum 6/25 50/18986 4.16891495875325e-11 6.46181818606753e-09 4.66625919944662e-09 HSPA5/SPCS1/SPCS2/SPCS3/SSR3/TRAM1 6
MeSH_gene2pubmed B_1_2 D014415 D014415 9/27 345/26076 4.25437313168237e-11 2.45477329698073e-08 1.84057616539101e-08 DNAJB11/DNAJC3/HDLBP/HSP90B1/HSPA5/LMAN1/LMAN2/PDIA4/SELENOS 9
MeSH_gene2pubmed B_1_2 D051702 Activating Transcription Factor 6 6/27 84/26076 2.612579330982e-10 8.23088299035256e-08 6.1714729709658e-08 DNAJB11/DNAJC3/HSP90B1/HSPA5/LMAN1/LMAN2 6