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Selected Module: B_1_1
Module Info
| Module_Name | B_1_1 |
| Cell_Type | B |
| Name | B_1_1: RNA, Nuclear |
| Meta_Module | B_1 |
| Gene_Number | 33 |
Genes:
EEF1A1, EEF1B2, NACA, RPL10, RPL11, RPL12, RPL13, RPL14, RPL18, RPL19, RPL24, RPL29, RPL3, RPL30, RPL32, RPL5, RPL7A, RPL8, RPLP1, RPS12, RPS13, RPS14, RPS15, RPS15A, RPS19, RPS23, RPS27A, RPS3, RPS4X, RPS5, RPS7, RPS8, RPS9
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| ZZZ3 | 7.91479601155885e-19 | EEF1A1/NACA/RPL11/RPL24/RPL29/RPL3/RPL32/RPL5/RPL8/RPS14/RPS15A/RPS23/RPS3/RPS4X/RPS7 |
| RUVBL1 | 1.37266720166462e-07 | EEF1A1/NACA/RPL11/RPL18/RPL24/RPS12/RPS14 |
| PSMB5 | 1.37266720166462e-07 | EEF1A1/RPL10/RPL12/RPL3/RPL32/RPLP1/RPS12/RPS9 |
| NPM1 | 8.44610226544066e-06 | RPL10/RPL12/RPL18/RPL7A/RPS19/RPS7/RPS8 |
| GTF2E2 | 1.69180553701949e-05 | EEF1A1/RPL10/RPL12/RPLP1/RPS12/RPS8/RPS9 |
| HJURP | 2.71150205332253e-05 | EEF1A1/RPL3/RPL7A/RPS15A |
| FOXR2 | 0.00017734117507332 | EEF1A1/RPL32/RPL8/RPS14/RPS5 |
| PER1 | 0.00017734117507332 | EEF1A1/RPL12/RPL3 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_1_1 | GO:1904666 | regulation of ubiquitin protein ligase activity | 3/33 | 21/18986 | 6.22841102359836e-06 | 0.00013507866407429 | 0.00010612884573105 | RPL11/RPL5/RPS7 | 3 |
| MeSH_gene2pubmed | B_1_1 | D006643 | Histidine-tRNA Ligase | 3/33 | 29/26076 | 6.59744879232397e-06 | 0.00013930041878649 | 0.00010317814652657 | EEF1A1/EEF1B2/RPL5 | 3 |
| MeSH_gene2pubmed | B_1_1 | D007935 | Leucine-tRNA Ligase | 3/33 | 34/26076 | 1.07578575437733e-05 | 0.00022083490902356 | 0.00016356976382345 | EEF1A1/EEF1B2/RPS14 | 3 |
| GO | B_1_1 | GO:0031397 | negative regulation of protein ubiquitination | 4/33 | 81/18986 | 1.14485632820949e-05 | 0.00023368537993452 | 0.0001836023461339 | RPL11/RPL5/RPS3/RPS7 | 4 |
| MeSH_gene2pubmed | B_1_1 | D010444 | Peptide Elongation Factor Tu | 3/33 | 39/26076 | 1.63591169829007e-05 | 0.00032674020136117 | 0.00024201254142555 | EEF1A1/RPS19/RPS7 | 3 |
| hallmark | B_1_1 | HALLMARK_MYC_TARGETS_V1 | HALLMARK_MYC_TARGETS_V1 | 5/9 | 200/4384 | 2.04023263387439e-05 | 8.16093053549757e-05 | 6.44283989644545e-05 | EEF1B2/RPL14/RPL18/RPS3/RPS5 | 5 |
| GO | B_1_1 | GO:1903321 | negative regulation of protein modification by small protein conjugation or removal | 4/33 | 94/18986 | 2.06535290081739e-05 | 0.00037991365672133 | 0.0002984912394686 | RPL11/RPL5/RPS3/RPS7 | 4 |
| GO | B_1_1 | GO:1901798 | positive regulation of signal transduction by p53 class mediator | 3/33 | 31/18986 | 2.08021886965572e-05 | 0.00037991365672133 | 0.0002984912394686 | RPL11/RPS15/RPS7 | 3 |
| GO | B_1_1 | GO:1901874 | negative regulation of post-translational protein modification | 4/33 | 98/18986 | 2.43457953453925e-05 | 0.00042239954924256 | 0.00033187163128719 | RPL11/RPL5/RPS3/RPS7 | 4 |
| MeSH_gene2pubmed | B_1_1 | D012336 | RNA, Ribosomal, 16S | 3/33 | 46/26076 | 2.70091647131439e-05 | 0.00051178904417982 | 0.00037907599597394 | EEF1A1/RPL14/RPS19 | 3 |