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Selected Module: B_14_7
Module Info
| Module_Name | B_14_7 |
| Cell_Type | B |
| Name | B_14_7: heme biosynthetic process |
| Meta_Module | B_18 |
| Gene_Number | 62 |
Genes:
ACTR8, AEN, AGPS, ATP6V1A, BLMH, BNIP1, C18orf21, C6orf226, CAPN15, CDK5, CETN2, CHAC2, COX11, CPSF1, DMAC2, FANCA, GATD3, GLYCTK, GSS, GSTZ1, GYPC, HLA-A, ITGB7, KDM1A, LIG1, MED24, METTL2A, METTL2B, MRPL45, MSRB1, MVB12A, NFE2L1, NMRAL1, PNKD, PRAF2, PTRH1, RFT1, RFXANK, RHOQ, RIOK2, SAP30, SETD3, SHARPIN, SHLD1, SLC16A1, SLC25A12, SMUG1, SRRD, STYXL1, TEX261, TFPT, TM7SF2, TMEM14B, TMEM230, TOMM34, TXNRD1, UQCC4, UQCRB, URM1, USB1, WDR13, YARS2
UMAP Visualizations
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Enriched TF
No TF enriched
Functional Enrichment Results
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enrichment_term
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module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_14_7 | GO:0006783 | heme biosynthetic process | 3/57 | 31/18986 | 0.00010863944731092 | 0.0384909127296725 | 0.0347397954866733 | NFE2L1/SRRD/TMEM14B | 3 |
| GO | B_14_7 | GO:0043247 | telomere maintenance in response to DNA damage | 3/57 | 33/18986 | 0.00013130537159946 | 0.0384909127296725 | 0.0347397954866733 | ACTR8/SHLD1/TFPT | 3 |
| GO | B_14_7 | GO:0006779 | porphyrin-containing compound biosynthetic process | 3/57 | 35/18986 | 0.00015684419353223 | 0.0384909127296725 | 0.0347397954866733 | NFE2L1/SRRD/TMEM14B | 3 |
| GO | B_14_7 | GO:0033014 | tetrapyrrole biosynthetic process | 3/57 | 35/18986 | 0.00015684419353223 | 0.0384909127296725 | 0.0347397954866733 | NFE2L1/SRRD/TMEM14B | 3 |
| GO | B_14_7 | GO:0022616 | DNA strand elongation | 3/57 | 37/18986 | 0.00018540902085584 | 0.0384909127296725 | 0.0347397954866733 | ACTR8/LIG1/TFPT | 3 |
| reactome | B_14_7 | R-HSA-5696399 | Global Genome Nucleotide Excision Repair (GG-NER) | 4/41 | 84/11146 | 0.00024581775467195 | 0.016109536823043 | 0.0153066861290208 | ACTR8/CETN2/LIG1/TFPT | 4 |
| reactome | B_14_7 | R-HSA-611105 | Respiratory electron transport | 5/41 | 158/11146 | 0.00026663689484811 | 0.016109536823043 | 0.0153066861290208 | COX11/DMAC2/PNKD/SLC25A12/UQCRB | 5 |
| reactome | B_14_7 | R-HSA-156590 | Glutathione conjugation | 3/41 | 36/11146 | 0.0003031957279238 | 0.016109536823043 | 0.0153066861290208 | CHAC2/GSS/GSTZ1 | 3 |
| reactome | B_14_7 | R-HSA-1428517 | Aerobic respiration and respiratory electron transport | 6/41 | 260/11146 | 0.00034448198095079 | 0.016109536823043 | 0.0153066861290208 | COX11/DMAC2/GSTZ1/PNKD/SLC25A12/UQCRB | 6 |
| reactome | B_14_7 | R-HSA-5696394 | DNA Damage Recognition in GG-NER | 3/41 | 38/11146 | 0.00035640568192573 | 0.016109536823043 | 0.0153066861290208 | ACTR8/CETN2/TFPT | 3 |