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Selected Module: B_14_46


Module Info

Module_Name B_14_46
Cell_Type B
Name B_14_46: Platelet activation, signaling and aggregation
Meta_Module B_30
Gene_Number 18

Genes:

CARD19, CAVIN2, CLU, EMP3, GNG11, GRAP2, H2AC6, MAP3K7CL, MFSD1, NCOA4, NRGN, PF4, PPBP, RGS18, RNF11, TMEM140, TUBA4A, TUBB1


UMAP Visualizations


UMAP for B_14_46

UMAP for B_14_46


Word Cloud

Enriched TF

Wordcloud for B_14_46
No TF enriched


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
reactome B_14_46 R-HSA-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 2/10 94/11146 0.00303034248016401 0.0163061285837397 0.00759484330868172 H2AC6/PF4 2
GO B_14_46 GO:0031983 vesicle lumen 3/18 330/19960 0.00303920725728379 0.0267450238640973 0.0166356607767113 CLU/PF4/PPBP 3
reactome B_14_46 R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 2/10 99/11146 0.0033550735597425 0.0176336424302745 0.00821315436901468 TUBA4A/TUBB1 2
WikiPathways B_14_46 WP5039 SARS CoV 2 innate immunity evasion and cell specific immune response 2/12 66/8836 0.00345590823095117 0.0329061496531697 0.0230920348443296 PF4/PPBP 2
reactome B_14_46 R-HSA-6807878 COPI-mediated anterograde transport 2/10 101/11146 0.00348936248126638 0.0179226345628682 0.00834775713221621 TUBA4A/TUBB1 2
WikiPathways B_14_46 WP2359 Parkin ubiquitin proteasomal system pathway 2/12 71/8836 0.00398862420038421 0.0329061496531697 0.0230920348443296 TUBA4A/TUBB1 2
reactome B_14_46 R-HSA-5610787 Hedgehog 'off' state 2/10 113/11146 0.00434735093930753 0.0218333624951889 0.0101692419632925 TUBA4A/TUBB1 2
reactome B_14_46 R-HSA-9648025 EML4 and NUDC in mitotic spindle formation 2/10 117/11146 0.00465307322121814 0.0228607510433761 0.0106477648082795 TUBA4A/TUBB1 2
reactome B_14_46 R-HSA-373760 L1CAM interactions 2/10 119/11146 0.00480959932889454 0.0231270095389397 0.0107717790120818 TUBA4A/TUBB1 2
reactome B_14_46 R-HSA-68886 M Phase 3/10 417/11146 0.00512614515863862 0.0236605592004446 0.011020288402629 H2AC6/TUBA4A/TUBB1 3