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Selected Module: B_14_46


Module Info

Module_Name B_14_46
Cell_Type B
Name B_14_46: Platelet activation, signaling and aggregation
Meta_Module B_30
Gene_Number 18

Genes:

CARD19, CAVIN2, CLU, EMP3, GNG11, GRAP2, H2AC6, MAP3K7CL, MFSD1, NCOA4, NRGN, PF4, PPBP, RGS18, RNF11, TMEM140, TUBA4A, TUBB1


UMAP Visualizations


UMAP for B_14_46

UMAP for B_14_46


Word Cloud

Enriched TF

Wordcloud for B_14_46
No TF enriched


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
reactome B_14_46 R-HSA-76002 Platelet activation, signaling and aggregation 5/10 263/11146 1.61098877514232e-06 0.00029877813062087 0.00013916075017273 CLU/GNG11/PF4/PPBP/TUBA4A 5
reactome B_14_46 R-HSA-114608 Platelet degranulation 4/10 129/11146 3.40781770309953e-06 0.00029877813062087 0.00013916075017273 CLU/PF4/PPBP/TUBA4A 4
reactome B_14_46 R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 4/10 134/11146 3.96608137992305e-06 0.00029877813062087 0.00013916075017273 CLU/PF4/PPBP/TUBA4A 4
MeSH_gene2pubmed B_14_46 D009185 Myelin Proteins 4/18 219/26076 1.35049227306956e-05 0.0121717245068219 0.00736423651434832 CLU/EMP3/NRGN/TUBA4A 4
GO B_14_46 GO:0061462 protein localization to lysosome 3/16 59/18986 1.55100709806034e-05 0.00445139037143317 0.00274283360499091 CLU/MFSD1/NCOA4 3
MeSH_gene2pubmed B_14_46 D005176 Factor XIII 3/18 75/26076 1.8077452328276e-05 0.0121717245068219 0.00736423651434832 PF4/PPBP/TUBB1 3
reactome B_14_46 R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 4/10 205/11146 2.13983177402144e-05 0.00120900495232212 0.00056311362474248 GNG11/NRGN/TUBA4A/TUBB1 4
MeSH_gene2pubmed B_14_46 D051096 Proto-Oncogene Proteins c-ret 4/18 258/26076 2.56867994183134e-05 0.0121717245068219 0.00736423651434832 CLU/GRAP2/NCOA4/RNF11 4
MeSH_gene2pubmed B_14_46 D002482 Cellulose 3/18 86/26076 2.72681731042954e-05 0.0121717245068219 0.00736423651434832 CLU/PF4/PPBP 3
GO B_14_46 GO:0031093 platelet alpha granule lumen 3/18 67/19960 2.84532632156559e-05 0.00125194358148886 0.00077872088800742 CLU/PF4/PPBP 3