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Selected Module: B_14_37
Module Info
| Module_Name | B_14_37 |
| Cell_Type | B |
| Name | B_14_37: IL9 signaling |
| Meta_Module | B_27 |
| Gene_Number | 35 |
Genes:
ARF6, BCL7C, BLOC1S4, CAPN12, CMPK1, CTDNEP1, CTDSP2, CTSZ, CXXC5, FNTA, HNRNPL, KHDRBS1, LRP10, LYL1, MAP2K1, MAP2K2, MT-CO1, PDCD7, PTOV1, PTP4A2, R3HDM4, RETREG2, RNF187, S1PR4, SART1, STAT5B, THAP11, TRIR, UNC93B1, URI1, USF2, VEGFB, WIPI2, YPEL3, ZNF688
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| AP2ALPHA | 0.00163940154936569 | CTDNEP1/CXXC5/HNRNPL/MAP2K2/THAP11 |
| AP2GAMMA | 0.00163940154936569 | CTDNEP1/CXXC5/HNRNPL/MAP2K2/THAP11 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_14_37 | R-HSA-169893 | Prolonged ERK activation events | 2/26 | 14/11146 | 0.00046802866103109 | 0.0229334043905238 | 0.016257837698975 | MAP2K1/MAP2K2 | 2 |
| KEGG | B_14_37 | hsa04014 | Ras signaling pathway | 4/14 | 238/8541 | 0.00047216078567777 | 0.00912844185643695 | 0.00323057379674266 | ARF6/MAP2K1/MAP2K2/VEGFB | 4 |
| MeSH_gene2pubmed | B_14_37 | D055293 | Receptors, Urokinase Plasminogen Activator | 4/34 | 281/26076 | 0.00047453462542805 | 0.0281965412915639 | 0.0188041394864021 | MAP2K1/MAP2K2/STAT5B/VEGFB | 4 |
| GO | B_14_37 | GO:0060438 | trachea development | 2/33 | 19/18986 | 0.00049179081094107 | 0.0394416230374741 | 0.0312675420850956 | MAP2K1/MAP2K2 | 2 |
| GO | B_14_37 | GO:2000641 | regulation of early endosome to late endosome transport | 2/33 | 19/18986 | 0.00049179081094107 | 0.0394416230374741 | 0.0312675420850956 | MAP2K1/MAP2K2 | 2 |
| WikiPathways | B_14_37 | WP2037 | Prolactin signaling | 3/19 | 74/8836 | 0.00049621991108738 | 0.00520037544695122 | 0.00201880943069402 | MAP2K1/MAP2K2/STAT5B | 3 |
| WikiPathways | B_14_37 | WP4928 | MAPK pathway in congenital thyroid cancer | 2/19 | 16/8836 | 0.00051634933515827 | 0.00520037544695122 | 0.00201880943069402 | MAP2K1/MAP2K2 | 2 |
| MeSH_gene2pubmed | B_14_37 | D015007 | D015007 | 2/34 | 26/26076 | 0.00052588004867717 | 0.0302709703019796 | 0.0201875663423111 | MAP2K1/MAP2K2 | 2 |
| GO | B_14_37 | GO:0016311 | dephosphorylation | 4/33 | 222/18986 | 0.00057052491725405 | 0.0415964530579773 | 0.0329757942604257 | CTDNEP1/CTDSP2/PTP4A2/URI1 | 4 |
| MeSH_gene2pubmed | B_14_37 | D008079 | Lipoproteins, VLDL | 3/34 | 125/26076 | 0.00057726047365722 | 0.0312444288645751 | 0.0208367612349044 | LRP10/MAP2K1/MAP2K2 | 3 |