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Selected Module: B_14_37


Module Info

Module_Name B_14_37
Cell_Type B
Name B_14_37: IL9 signaling
Meta_Module B_27
Gene_Number 35

Genes:

ARF6, BCL7C, BLOC1S4, CAPN12, CMPK1, CTDNEP1, CTDSP2, CTSZ, CXXC5, FNTA, HNRNPL, KHDRBS1, LRP10, LYL1, MAP2K1, MAP2K2, MT-CO1, PDCD7, PTOV1, PTP4A2, R3HDM4, RETREG2, RNF187, S1PR4, SART1, STAT5B, THAP11, TRIR, UNC93B1, URI1, USF2, VEGFB, WIPI2, YPEL3, ZNF688


UMAP Visualizations


UMAP for B_14_37

UMAP for B_14_37


Word Cloud

Enriched TF

Wordcloud for B_14_37
TF p.adjust Genes
AP2ALPHA 0.00163940154936569 CTDNEP1/CXXC5/HNRNPL/MAP2K2/THAP11
AP2GAMMA 0.00163940154936569 CTDNEP1/CXXC5/HNRNPL/MAP2K2/THAP11


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
WikiPathways B_14_37 WP286 IL3 signaling 2/19 49/8836 0.00485080755449641 0.0151991970040888 0.00590039749318862 MAP2K1/STAT5B 2
KEGG B_14_37 hsa04929 GnRH secretion 2/14 65/8541 0.00489268112862654 0.0240808877597733 0.00852227425255136 MAP2K1/MAP2K2 2
KEGG B_14_37 hsa04720 Long-term potentiation 2/14 67/8541 0.00519110469504655 0.0240808877597733 0.00852227425255136 MAP2K1/MAP2K2 2
KEGG B_14_37 hsa05166 Human T-cell leukemia virus 1 infection 3/14 224/8541 0.00523081216722616 0.0240808877597733 0.00852227425255136 MAP2K1/MAP2K2/STAT5B 3
reactome B_14_37 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 2/26 47/11146 0.00530311400678527 0.0433087643887463 0.0307022389866515 MAP2K1/MAP2K2 2
reactome B_14_37 R-HSA-6802949 Signaling by RAS mutants 2/26 47/11146 0.00530311400678527 0.0433087643887463 0.0307022389866515 MAP2K1/MAP2K2 2
reactome B_14_37 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 2/26 47/11146 0.00530311400678527 0.0433087643887463 0.0307022389866515 MAP2K1/MAP2K2 2
reactome B_14_37 R-HSA-9649948 Signaling downstream of RAS mutants 2/26 47/11146 0.00530311400678527 0.0433087643887463 0.0307022389866515 MAP2K1/MAP2K2 2
WikiPathways B_14_37 WP4747 Netrin UNC5B signaling 2/19 52/8836 0.0054485875340122 0.0167011052672983 0.00648344512056372 MAP2K1/MAP2K2 2
KEGG B_14_37 hsa04664 Fc epsilon RI signaling pathway 2/14 69/8541 0.00549777009650116 0.0240808877597733 0.00852227425255136 MAP2K1/MAP2K2 2