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Selected Module: B_14_24
Module Info
| Module_Name | B_14_24 |
| Cell_Type | B |
| Name | B_14_24: DNA-templated DNA replication |
| Meta_Module | B_9 |
| Gene_Number | 31 |
Genes:
ATAD5, CENPK, CHAF1A, CKAP5, CSE1L, DDX11, DHFR, FEN1, FN3KRP, GMNN, H2AC20, HELLS, LMNB1, MAD2L1, MIS18A, MMS22L, ORC6, PHF19, POLD3, PRIM1, RFC3, RFC4, RRM1, SAAL1, SKP2, TEX30, TOPBP1, TTF2, UBE2T, UNG, YEATS4
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| SGCGSSAAA | 8.60315355022546e-05 | ATAD5/GMNN/POLD3/TOPBP1/UNG |
| KTGGYRSGAA | 8.60315355022546e-05 | MMS22L/PRIM1/RFC4/TOPBP1 |
| E2F1DP1RB | 8.60315355022546e-05 | ATAD5/GMNN/POLD3/TOPBP1/UNG |
| E2F | 8.60315355022546e-05 | ATAD5/GMNN/POLD3/TOPBP1/UNG |
| E2F1 | 8.60315355022546e-05 | ATAD5/GMNN/POLD3/TOPBP1/UNG |
| E2F | 8.60315355022546e-05 | ATAD5/GMNN/POLD3/TOPBP1/UNG |
| E2F | 8.60315355022546e-05 | ATAD5/GMNN/POLD3/TOPBP1/UNG |
| E2F1DP1 | 8.60315355022546e-05 | ATAD5/GMNN/POLD3/TOPBP1/UNG |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_14_24 | R-HSA-9821002 | Chromatin modifications during the maternal to zygotic transition (MZT) | 2/24 | 70/11146 | 0.00981508014374538 | 0.0283679755374104 | 0.0154974949638085 | H2AC20/UNG | 2 |
| reactome | B_14_24 | R-HSA-68949 | Orc1 removal from chromatin | 2/24 | 71/11146 | 0.0100863738630058 | 0.0288008506690647 | 0.0157339757152785 | ORC6/SKP2 | 2 |
| reactome | B_14_24 | R-HSA-212300 | PRC2 methylates histones and DNA | 2/24 | 72/11146 | 0.0103609965950379 | 0.0288888963885176 | 0.0157820753088504 | H2AC20/PHF19 | 2 |
| reactome | B_14_24 | R-HSA-9710421 | Defective pyroptosis | 2/24 | 72/11146 | 0.0103609965950379 | 0.0288888963885176 | 0.0157820753088504 | H2AC20/PRIM1 | 2 |
| WikiPathways | B_14_24 | WP45 | G1 to S cell cycle control | 2/22 | 64/8836 | 0.0108675436711036 | 0.0389420314881212 | 0.0181125727851726 | ORC6/PRIM1 | 2 |
| reactome | B_14_24 | R-HSA-1221632 | Meiotic synapsis | 2/24 | 78/11146 | 0.0120778417848411 | 0.03328428491869 | 0.0181832868976188 | H2AC20/LMNB1 | 2 |
| reactome | B_14_24 | R-HSA-2559586 | DNA Damage/Telomere Stress Induced Senescence | 2/24 | 79/11146 | 0.0123753682460357 | 0.0337122100495456 | 0.0184170634514506 | H2AC20/LMNB1 | 2 |
| reactome | B_14_24 | R-HSA-174143 | APC/C-mediated degradation of cell cycle proteins | 2/24 | 87/11146 | 0.0148701626142587 | 0.0395980734784192 | 0.0216325251514349 | MAD2L1/SKP2 | 2 |
| reactome | B_14_24 | R-HSA-453276 | Regulation of mitotic cell cycle | 2/24 | 87/11146 | 0.0148701626142587 | 0.0395980734784192 | 0.0216325251514349 | MAD2L1/SKP2 | 2 |