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Selected Module: B_14_24


Module Info

Module_Name B_14_24
Cell_Type B
Name B_14_24: DNA-templated DNA replication
Meta_Module B_9
Gene_Number 31

Genes:

ATAD5, CENPK, CHAF1A, CKAP5, CSE1L, DDX11, DHFR, FEN1, FN3KRP, GMNN, H2AC20, HELLS, LMNB1, MAD2L1, MIS18A, MMS22L, ORC6, PHF19, POLD3, PRIM1, RFC3, RFC4, RRM1, SAAL1, SKP2, TEX30, TOPBP1, TTF2, UBE2T, UNG, YEATS4


UMAP Visualizations


UMAP for B_14_24

UMAP for B_14_24


Word Cloud

Enriched TF

Wordcloud for B_14_24
TF p.adjust Genes
SGCGSSAAA 8.60315355022546e-05 ATAD5/GMNN/POLD3/TOPBP1/UNG
KTGGYRSGAA 8.60315355022546e-05 MMS22L/PRIM1/RFC4/TOPBP1
E2F1DP1RB 8.60315355022546e-05 ATAD5/GMNN/POLD3/TOPBP1/UNG
E2F 8.60315355022546e-05 ATAD5/GMNN/POLD3/TOPBP1/UNG
E2F1 8.60315355022546e-05 ATAD5/GMNN/POLD3/TOPBP1/UNG
E2F 8.60315355022546e-05 ATAD5/GMNN/POLD3/TOPBP1/UNG
E2F 8.60315355022546e-05 ATAD5/GMNN/POLD3/TOPBP1/UNG
E2F1DP1 8.60315355022546e-05 ATAD5/GMNN/POLD3/TOPBP1/UNG


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
MeSH_gene2pubmed B_14_24 D018744 DNA, Plant 2/31 80/26076 0.00407981411601221 0.0489577693921466 0.0317735983418544 CHAF1A/TOPBP1 2
GO B_14_24 GO:0016447 somatic recombination of immunoglobulin gene segments 2/30 63/18986 0.0044399850176538 0.0400405921592052 0.0260025916823361 ATAD5/UNG 2
reactome B_14_24 R-HSA-5633007 Regulation of TP53 Activity 3/24 160/11146 0.00470861111623146 0.0152868607472172 0.00835124970867296 RFC3/RFC4/TOPBP1 3
reactome B_14_24 R-HSA-195258 RHO GTPase Effectors 4/24 326/11146 0.00480447974802922 0.0153873202740936 0.00840613099584059 CENPK/CKAP5/H2AC20/MAD2L1 4
GO B_14_24 GO:0070534 protein K63-linked ubiquitination 2/30 66/18986 0.00486218604265821 0.0427824800193814 0.0277831894862706 SKP2/UBE2T 2
GO B_14_24 GO:0009314 response to radiation 4/30 442/18986 0.0049165350022273 0.0427824800193814 0.0277831894862706 FEN1/POLD3/RRM1/TOPBP1 4
GO B_14_24 GO:0016445 somatic diversification of immunoglobulins 2/30 68/18986 0.00515357012192028 0.0440719100081458 0.0286205527642034 ATAD5/UNG 2
GO B_14_24 GO:0006282 regulation of DNA repair 3/30 227/18986 0.00539686959359839 0.0453702935326237 0.0294637305199127 DDX11/SKP2/YEATS4 3
GO B_14_24 GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 2/30 72/18986 0.00575991601459937 0.0468347269383817 0.0304147420270476 ATAD5/UNG 2
GO B_14_24 GO:0016444 somatic cell DNA recombination 2/30 72/18986 0.00575991601459937 0.0468347269383817 0.0304147420270476 ATAD5/UNG 2