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Selected Module: B_14_23
Module Info
| Module_Name | B_14_23 |
| Cell_Type | B |
| Name | B_14_23: ras GTPase-Activating Proteins |
| Meta_Module | B_6 |
| Gene_Number | 31 |
Genes:
AAGAB, ANKRD36C, ARHGAP26, CASP8, CBL, CRACR2A, DGKZ, DIAPH1, DIP2A, GAK, GFOD1, GTDC1, IL2RG, LNPK, MINDY2, MTMR12, NPLOC4, NUP93, PPP2R5C, PREX1, PRORP, RASA3, RASGRP1, RFWD3, SACM1L, SASH3, SOAT1, TGFB1, TMEM127, ZBTB7A, ZNFX1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| ELK1 | 0.0347907857235609 | DGKZ/SASH3/TMEM127/ZNFX1 |
| ETS2 | 0.0347907857235609 | DGKZ/RASA3/ZBTB7A/ZNFX1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_14_23 | GO:0051251 | positive regulation of lymphocyte activation | 4/29 | 336/18986 | 0.00161327545421565 | 0.0404249599392883 | 0.0291957136856031 | IL2RG/RASGRP1/SASH3/TGFB1 | 4 |
| GO | B_14_23 | GO:0046839 | phospholipid dephosphorylation | 2/29 | 40/18986 | 0.00169501844984019 | 0.0409001674100327 | 0.0295389180147588 | MTMR12/SACM1L | 2 |
| GO | B_14_23 | GO:0060391 | positive regulation of SMAD protein signal transduction | 2/29 | 40/18986 | 0.00169501844984019 | 0.0409001674100327 | 0.0295389180147588 | NUP93/TGFB1 | 2 |
| GO | B_14_23 | GO:0002705 | positive regulation of leukocyte mediated immunity | 3/29 | 158/18986 | 0.00176271317064049 | 0.041760277478992 | 0.0301601066900019 | RASGRP1/SASH3/TGFB1 | 3 |
| GO | B_14_23 | GO:0045066 | regulatory T cell differentiation | 2/29 | 42/18986 | 0.00186750407070618 | 0.0434528179308956 | 0.031382493218258 | IL2RG/TGFB1 | 2 |
| hallmark | B_14_23 | HALLMARK_INTERFERON_GAMMA_RESPONSE | HALLMARK_INTERFERON_GAMMA_RESPONSE | 3/8 | 200/4384 | 0.00441828281473045 | 0.039764545332574 | 0.0325557681085401 | CASP8/NUP93/ZNFX1 | 3 |
| onek1k | B_14_23 | CD4 CTL | CD4 CTL | 2/20 | 75/6471 | 0.0220070958137367 | 0.0440141916274734 | 0.0231653640144597 | PPP2R5C/RASGRP1 | 2 |