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Selected Module: B_14_23


Module Info

Module_Name B_14_23
Cell_Type B
Name B_14_23: ras GTPase-Activating Proteins
Meta_Module B_6
Gene_Number 31

Genes:

AAGAB, ANKRD36C, ARHGAP26, CASP8, CBL, CRACR2A, DGKZ, DIAPH1, DIP2A, GAK, GFOD1, GTDC1, IL2RG, LNPK, MINDY2, MTMR12, NPLOC4, NUP93, PPP2R5C, PREX1, PRORP, RASA3, RASGRP1, RFWD3, SACM1L, SASH3, SOAT1, TGFB1, TMEM127, ZBTB7A, ZNFX1


UMAP Visualizations


UMAP for B_14_23

UMAP for B_14_23


Word Cloud

Enriched TF

Wordcloud for B_14_23
TF p.adjust Genes
ELK1 0.0347907857235609 DGKZ/SASH3/TMEM127/ZNFX1
ETS2 0.0347907857235609 DGKZ/RASA3/ZBTB7A/ZNFX1


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_14_23 GO:0033081 regulation of T cell differentiation in thymus 2/29 28/18986 0.00083081235027594 0.0331896309761647 0.023970214559673 IL2RG/RASGRP1 2
GO B_14_23 GO:0045785 positive regulation of cell adhesion 5/29 499/18986 0.00086608741376446 0.0331896309761647 0.023970214559673 IL2RG/PREX1/RASGRP1/SASH3/TGFB1 5
GO B_14_23 GO:1903039 positive regulation of leukocyte cell-cell adhesion 4/29 284/18986 0.00086692612780691 0.0331896309761647 0.023970214559673 IL2RG/RASGRP1/SASH3/TGFB1 4
GO B_14_23 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway 2/29 29/18986 0.00089150965784018 0.0331896309761647 0.023970214559673 CBL/TGFB1 2
GO B_14_23 GO:0035710 CD4-positive, alpha-beta T cell activation 3/29 129/18986 0.00098400344500021 0.0350102737399463 0.0252851191368195 CRACR2A/IL2RG/SASH3 3
GO B_14_23 GO:1901186 positive regulation of ERBB signaling pathway 2/29 31/18986 0.00101913289636212 0.0350102737399463 0.0252851191368195 CBL/TGFB1 2
GO B_14_23 GO:0000077 DNA damage checkpoint signaling 3/29 131/18986 0.00102874573503732 0.0350102737399463 0.0252851191368195 DGKZ/PPP2R5C/RFWD3 3
GO B_14_23 GO:0046632 alpha-beta T cell differentiation 3/29 133/18986 0.00107475897896996 0.0350102737399463 0.0252851191368195 CRACR2A/IL2RG/SASH3 3
GO B_14_23 GO:0050864 regulation of B cell activation 3/29 133/18986 0.00107475897896996 0.0350102737399463 0.0252851191368195 IL2RG/SASH3/TGFB1 3
GO B_14_23 GO:0002708 positive regulation of lymphocyte mediated immunity 3/29 136/18986 0.00114619253811237 0.0364265579795224 0.0263079879094341 RASGRP1/SASH3/TGFB1 3