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Selected Module: B_14_23


Module Info

Module_Name B_14_23
Cell_Type B
Name B_14_23: ras GTPase-Activating Proteins
Meta_Module B_6
Gene_Number 31

Genes:

AAGAB, ANKRD36C, ARHGAP26, CASP8, CBL, CRACR2A, DGKZ, DIAPH1, DIP2A, GAK, GFOD1, GTDC1, IL2RG, LNPK, MINDY2, MTMR12, NPLOC4, NUP93, PPP2R5C, PREX1, PRORP, RASA3, RASGRP1, RFWD3, SACM1L, SASH3, SOAT1, TGFB1, TMEM127, ZBTB7A, ZNFX1


UMAP Visualizations


UMAP for B_14_23

UMAP for B_14_23


Word Cloud

Enriched TF

Wordcloud for B_14_23
TF p.adjust Genes
ELK1 0.0347907857235609 DGKZ/SASH3/TMEM127/ZNFX1
ETS2 0.0347907857235609 DGKZ/RASA3/ZBTB7A/ZNFX1


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_14_23 GO:1903706 regulation of hemopoiesis 5/29 433/18986 0.00045557301401064 0.0269823471479942 0.0194871901686851 CASP8/IL2RG/RASGRP1/SASH3/TGFB1 5
GO B_14_23 GO:0043367 CD4-positive, alpha-beta T cell differentiation 3/29 102/18986 0.00049696816179212 0.0279108379463208 0.0201577647728002 CRACR2A/IL2RG/SASH3 3
GO B_14_23 GO:0002274 myeloid leukocyte activation 4/29 247/18986 0.00051409064521235 0.0279108379463208 0.0201577647728002 CBL/PREX1/RASGRP1/TGFB1 4
GO B_14_23 GO:0010720 positive regulation of cell development 5/29 460/18986 0.00059988583670236 0.0300822063318892 0.0217259704008635 CASP8/IL2RG/RASGRP1/SASH3/TGFB1 5
GO B_14_23 GO:0045591 positive regulation of regulatory T cell differentiation 2/29 24/18986 0.00060892675633986 0.0300822063318892 0.0217259704008635 IL2RG/TGFB1 2
GO B_14_23 GO:0050870 positive regulation of T cell activation 4/29 260/18986 0.00062334579505833 0.0300822063318892 0.0217259704008635 IL2RG/RASGRP1/SASH3/TGFB1 4
GO B_14_23 GO:0045088 regulation of innate immune response 5/29 470/18986 0.00066125001148508 0.0307717416058952 0.022223966551416 CASP8/NPLOC4/RASGRP1/TGFB1/ZNFX1 5
GO B_14_23 GO:0045649 regulation of macrophage differentiation 2/29 27/18986 0.00077219932697764 0.0331896309761647 0.023970214559673 CASP8/TGFB1 2
GO B_14_23 GO:0046856 phosphatidylinositol dephosphorylation 2/29 27/18986 0.00077219932697764 0.0331896309761647 0.023970214559673 MTMR12/SACM1L 2
GO B_14_23 GO:0007264 small GTPase-mediated signal transduction 5/29 491/18986 0.00080539526582989 0.0331896309761647 0.023970214559673 ARHGAP26/CBL/PREX1/RASA3/RASGRP1 5