Module Explorer
Instructions
- Enter a module name.
- Click Submit to search for the detailed information of the module.
- Results will appear below if available.
Selected Module: B_14_23
Module Info
| Module_Name | B_14_23 |
| Cell_Type | B |
| Name | B_14_23: ras GTPase-Activating Proteins |
| Meta_Module | B_6 |
| Gene_Number | 31 |
Genes:
AAGAB, ANKRD36C, ARHGAP26, CASP8, CBL, CRACR2A, DGKZ, DIAPH1, DIP2A, GAK, GFOD1, GTDC1, IL2RG, LNPK, MINDY2, MTMR12, NPLOC4, NUP93, PPP2R5C, PREX1, PRORP, RASA3, RASGRP1, RFWD3, SACM1L, SASH3, SOAT1, TGFB1, TMEM127, ZBTB7A, ZNFX1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| ELK1 | 0.0347907857235609 | DGKZ/SASH3/TMEM127/ZNFX1 |
| ETS2 | 0.0347907857235609 | DGKZ/RASA3/ZBTB7A/ZNFX1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_14_23 | R-HSA-9013026 | RHOB GTPase cycle | 3/20 | 70/11146 | 0.00025050329879202 | 0.0269702976783179 | 0.0194791239474598 | ARHGAP26/DIAPH1/PREX1 | 3 |
| reactome | B_14_23 | R-HSA-9013106 | RHOC GTPase cycle | 3/20 | 74/11146 | 0.00029529523005457 | 0.0269702976783179 | 0.0194791239474598 | ARHGAP26/DIAPH1/PREX1 | 3 |
| GO | B_14_23 | GO:0050871 | positive regulation of B cell activation | 3/29 | 86/18986 | 0.00030111157659283 | 0.0231682156396048 | 0.01673254819389 | IL2RG/SASH3/TGFB1 | 3 |
| GO | B_14_23 | GO:0045651 | positive regulation of macrophage differentiation | 2/29 | 17/18986 | 0.00030204705649152 | 0.0231682156396048 | 0.01673254819389 | CASP8/TGFB1 | 2 |
| GO | B_14_23 | GO:0044773 | mitotic DNA damage checkpoint signaling | 3/29 | 87/18986 | 0.00031154593387518 | 0.0231682156396048 | 0.01673254819389 | DGKZ/PPP2R5C/RFWD3 | 3 |
| GO | B_14_23 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle | 3/29 | 89/18986 | 0.00033310930464066 | 0.0231682156396048 | 0.01673254819389 | DGKZ/PPP2R5C/RFWD3 | 3 |
| GO | B_14_23 | GO:0045619 | regulation of lymphocyte differentiation | 4/29 | 223/18986 | 0.00034938756486898 | 0.0231682156396048 | 0.01673254819389 | IL2RG/RASGRP1/SASH3/TGFB1 | 4 |
| GO | B_14_23 | GO:0044774 | mitotic DNA integrity checkpoint signaling | 3/29 | 91/18986 | 0.00035561344036231 | 0.0231682156396048 | 0.01673254819389 | DGKZ/PPP2R5C/RFWD3 | 3 |
| hallmark | B_14_23 | HALLMARK_IL6_JAK_STAT3_SIGNALING | HALLMARK_IL6_JAK_STAT3_SIGNALING | 3/8 | 87/4384 | 0.00039346631357518 | 0.00708239364435335 | 0.00579845093689748 | CBL/IL2RG/TGFB1 | 3 |
| GO | B_14_23 | GO:1902807 | negative regulation of cell cycle G1/S phase transition | 3/29 | 98/18986 | 0.00044203503970161 | 0.0269823471479942 | 0.0194871901686851 | DGKZ/PPP2R5C/RFWD3 | 3 |