Module Explorer

Instructions


  • Enter a module name.
  • Click Submit to search for the detailed information of the module.
  • Results will appear below if available.

Selected Module: B_14_23


Module Info

Module_Name B_14_23
Cell_Type B
Name B_14_23: ras GTPase-Activating Proteins
Meta_Module B_6
Gene_Number 31

Genes:

AAGAB, ANKRD36C, ARHGAP26, CASP8, CBL, CRACR2A, DGKZ, DIAPH1, DIP2A, GAK, GFOD1, GTDC1, IL2RG, LNPK, MINDY2, MTMR12, NPLOC4, NUP93, PPP2R5C, PREX1, PRORP, RASA3, RASGRP1, RFWD3, SACM1L, SASH3, SOAT1, TGFB1, TMEM127, ZBTB7A, ZNFX1


UMAP Visualizations


UMAP for B_14_23

UMAP for B_14_23


Word Cloud

Enriched TF

Wordcloud for B_14_23
TF p.adjust Genes
ELK1 0.0347907857235609 DGKZ/SASH3/TMEM127/ZNFX1
ETS2 0.0347907857235609 DGKZ/RASA3/ZBTB7A/ZNFX1


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
MeSH_gene2pubmed B_14_23 D020703 ras GTPase-Activating Proteins 7/31 313/26076 6.89565644716152e-08 0.00022865996778787 0.00017014124960154 ARHGAP26/CBL/DIAPH1/DIP2A/RASA3/RASGRP1/TGFB1 7
MeSH_gene2pubmed B_14_23 D006153 Guanosine Diphosphate 7/31 424/26076 5.36913917907336e-07 0.00089020327589036 0.0006623822229341 CASP8/CBL/DIAPH1/PREX1/RASA3/RASGRP1/TGFB1 7
GO B_14_23 GO:0030098 lymphocyte differentiation 7/29 426/18986 2.77525784892665e-06 0.00246209596199744 0.00177817489197052 CRACR2A/IL2RG/PREX1/RASGRP1/SASH3/TGFB1/ZBTB7A 7
GO B_14_23 GO:0042113 B cell activation 6/29 284/18986 3.77911889792393e-06 0.00246209596199744 0.00177817489197052 CASP8/IL2RG/RASGRP1/SASH3/TGFB1/ZBTB7A 6
MeSH_gene2pubmed B_14_23 D019852 Diacylglycerol Kinase 4/31 106/26076 7.45795732522761e-06 0.00824352883015159 0.00613384279660825 CASP8/DGKZ/GAK/RASGRP1 4
GO B_14_23 GO:0030217 T cell differentiation 6/29 320/18986 7.4925807074982e-06 0.00274982912283175 0.00198598152911224 CRACR2A/IL2RG/PREX1/RASGRP1/SASH3/TGFB1 6
GO B_14_23 GO:1902107 positive regulation of leukocyte differentiation 5/29 195/18986 1.05519152833145e-05 0.00274982912283175 0.00198598152911224 CASP8/IL2RG/RASGRP1/SASH3/TGFB1 5
GO B_14_23 GO:1903708 positive regulation of hemopoiesis 5/29 195/18986 1.05519152833145e-05 0.00274982912283175 0.00198598152911224 CASP8/IL2RG/RASGRP1/SASH3/TGFB1 5
GO B_14_23 GO:0031571 mitotic G1 DNA damage checkpoint signaling 3/29 33/18986 1.69502840501788e-05 0.00315517430248329 0.00227872991591878 DGKZ/PPP2R5C/RFWD3 3
GO B_14_23 GO:0044819 mitotic G1/S transition checkpoint signaling 3/29 33/18986 1.69502840501788e-05 0.00315517430248329 0.00227872991591878 DGKZ/PPP2R5C/RFWD3 3