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Selected Module: B_14_22
Module Info
| Module_Name | B_14_22 |
| Cell_Type | B |
| Name | B_14_22: Processing of Capped Intron-Containing Pre-mRNA |
| Meta_Module | B_3 |
| Gene_Number | 44 |
Genes:
AAMP, ADPRS, ARPC1A, BAX, CDK9, CISD3, CZIB, DTD1, ECHDC1, EED, ELP5, EMG1, ERI3, GLRX2, GPN1, GTF2E2, GTF2H5, HAUS1, HTATSF1, ITGB3BP, MAP7D1, MPHOSPH6, NPRL2, PCBP1, PIN4, PLRG1, PRKD2, PRPF19, PSMG2, RAB11B, RAE1, RALA, RBFA, SF3B4, SIT1, SNRNP70, SRRT, SURF2, SZRD1, TAF10, TMSB10, TRAF7, USP39, ZCCHC17
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| GABP | 0.00099194550588209 | CDK9/EMG1/PCBP1/RAB11B/SF3B4/TAF10 |
| MCM2 | 0.0499319310762962 | AAMP/NPRL2/RALA |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_14_22 | GO:0016591 | RNA polymerase II, holoenzyme | 3/41 | 87/19960 | 0.00075642455778194 | 0.00968223433960885 | 0.00644951465056182 | GTF2E2/GTF2H5/TAF10 | 3 |
| reactome | B_14_22 | R-HSA-6807505 | RNA polymerase II transcribes snRNA genes | 3/28 | 74/11146 | 0.00081684366855058 | 0.0119803738054086 | 0.0102607029242495 | CDK9/GTF2E2/SRRT | 3 |
| GO | B_14_22 | GO:0032806 | carboxy-terminal domain protein kinase complex | 2/41 | 21/19960 | 0.00084337236604317 | 0.00981378753213873 | 0.00653714465545425 | CDK9/GTF2H5 | 2 |
| GO | B_14_22 | GO:0043601 | nuclear replisome | 2/41 | 22/19960 | 0.00092650393818529 | 0.00988270867397652 | 0.00658305429763239 | PLRG1/PRPF19 | 2 |
| GO | B_14_22 | GO:0035861 | site of double-strand break | 3/41 | 99/19960 | 0.00110040481307104 | 0.010094782281158 | 0.00672432043399506 | ARPC1A/HTATSF1/PRPF19 | 3 |
| GO | B_14_22 | GO:0030894 | replisome | 2/41 | 24/19960 | 0.00110411681200166 | 0.010094782281158 | 0.00672432043399506 | PLRG1/PRPF19 | 2 |
| GO | B_14_22 | GO:0055029 | nuclear DNA-directed RNA polymerase complex | 3/41 | 111/19960 | 0.00152988034466321 | 0.0113851013244111 | 0.00758382571774093 | GTF2E2/GTF2H5/TAF10 | 3 |
| GO | B_14_22 | GO:0016607 | nuclear speck | 5/41 | 416/19960 | 0.00155139448128115 | 0.0113851013244111 | 0.00758382571774093 | PCBP1/PLRG1/PRPF19/SNRNP70/SURF2 | 5 |
| GO | B_14_22 | GO:0005686 | U2 snRNP | 2/41 | 29/19960 | 0.00161365192659731 | 0.0113851013244111 | 0.00758382571774093 | HTATSF1/SF3B4 | 2 |
| GO | B_14_22 | GO:0000428 | DNA-directed RNA polymerase complex | 3/41 | 114/19960 | 0.0016514537578335 | 0.0113851013244111 | 0.00758382571774093 | GTF2E2/GTF2H5/TAF10 | 3 |