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Selected Module: B_14_22
Module Info
| Module_Name | B_14_22 |
| Cell_Type | B |
| Name | B_14_22: Processing of Capped Intron-Containing Pre-mRNA |
| Meta_Module | B_3 |
| Gene_Number | 44 |
Genes:
AAMP, ADPRS, ARPC1A, BAX, CDK9, CISD3, CZIB, DTD1, ECHDC1, EED, ELP5, EMG1, ERI3, GLRX2, GPN1, GTF2E2, GTF2H5, HAUS1, HTATSF1, ITGB3BP, MAP7D1, MPHOSPH6, NPRL2, PCBP1, PIN4, PLRG1, PRKD2, PRPF19, PSMG2, RAB11B, RAE1, RALA, RBFA, SF3B4, SIT1, SNRNP70, SRRT, SURF2, SZRD1, TAF10, TMSB10, TRAF7, USP39, ZCCHC17
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| GABP | 0.00099194550588209 | CDK9/EMG1/PCBP1/RAB11B/SF3B4/TAF10 |
| MCM2 | 0.0499319310762962 | AAMP/NPRL2/RALA |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_14_22 | R-HSA-72203 | Processing of Capped Intron-Containing Pre-mRNA | 9/28 | 285/11146 | 1.85754919603976e-08 | 2.75239158435938e-06 | 2.35731145263316e-06 | HTATSF1/PCBP1/PLRG1/PRPF19/RAE1/SF3B4/SNRNP70/SRRT/USP39 | 9 |
| reactome | B_14_22 | R-HSA-72163 | mRNA Splicing - Major Pathway | 8/28 | 207/11146 | 2.79282054668462e-08 | 2.75239158435938e-06 | 2.35731145263316e-06 | HTATSF1/PCBP1/PLRG1/PRPF19/SF3B4/SNRNP70/SRRT/USP39 | 8 |
| MeSH_gene2pubmed | B_14_22 | D017381 | Spliceosomes | 9/44 | 422/26076 | 3.00378732145865e-08 | 8.25140377204692e-05 | 7.11423312977049e-05 | CDK9/EED/PCBP1/PLRG1/PRPF19/SF3B4/SNRNP70/SRRT/USP39 | 9 |
| reactome | B_14_22 | R-HSA-72172 | mRNA Splicing | 8/28 | 215/11146 | 3.75326125139916e-08 | 2.75239158435938e-06 | 2.35731145263316e-06 | HTATSF1/PCBP1/PLRG1/PRPF19/SF3B4/SNRNP70/SRRT/USP39 | 8 |
| GO | B_14_22 | GO:0022613 | ribonucleoprotein complex biogenesis | 10/42 | 492/18986 | 8.71423190141887e-08 | 6.5095312303599e-05 | 5.71470155219364e-05 | EMG1/ERI3/GTF2H5/HTATSF1/MPHOSPH6/PIN4/PRPF19/RBFA/SF3B4/USP39 | 10 |
| MeSH_gene2pubmed | B_14_22 | D012331 | RNA, Fungal | 6/44 | 188/26076 | 7.28829518303057e-07 | 0.00069597351284664 | 0.00060005763374588 | EMG1/HTATSF1/RAE1/SF3B4/SNRNP70/USP39 | 6 |
| MeSH_gene2pubmed | B_14_22 | D034441 | Heterogeneous-Nuclear Ribonucleoproteins | 8/44 | 450/26076 | 7.60073002744791e-07 | 0.00069597351284664 | 0.00060005763374588 | BAX/CDK9/GTF2E2/HTATSF1/PCBP1/RAE1/SNRNP70/TAF10 | 8 |
| GO | B_14_22 | GO:0005684 | U2-type spliceosomal complex | 5/41 | 95/19960 | 1.43709855323799e-06 | 0.00018394861481446 | 0.00012253156085502 | HTATSF1/PLRG1/PRPF19/SF3B4/SNRNP70 | 5 |
| GO | B_14_22 | GO:0005681 | spliceosomal complex | 6/41 | 207/19960 | 3.844169786212e-06 | 0.00024602686631756 | 0.00016388302772798 | HTATSF1/PLRG1/PRPF19/SF3B4/SNRNP70/USP39 | 6 |
| MeSH_gene2pubmed | B_14_22 | D017413 | Ribonucleoprotein, U2 Small Nuclear | 5/44 | 156/26076 | 6.46438230164948e-06 | 0.00443941454565778 | 0.0038275947838714 | HTATSF1/PCBP1/SF3B4/SNRNP70/TAF10 | 5 |