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Selected Module: B_14_21


Module Info

Module_Name B_14_21
Cell_Type B
Name B_14_21: Immunologic Factors
Meta_Module B_10
Gene_Number 40

Genes:

AP2A1, ASAH1, CASP1, CD14, CFD, CNIH4, CPPED1, DUSP6, FCGR3A, FGL2, GABARAP, GLUL, GNS, GRINA, IFITM3, IL17RA, IRAK3, ITPK1, LEPROT, LY96, MAPKAPK3, MBOAT7, NAPRT, NEAT1, PICALM, PTTG1IP, RHOC, RNF144B, S100A12, SERPINA1, SH2B3, SLC7A7, SPI1, TBXAS1, TCIRG1, TSPO, VCAN, ZDHHC7, ZFAND5, ZYX


UMAP Visualizations


UMAP for B_14_21

UMAP for B_14_21


Word Cloud

Enriched TF

Wordcloud for B_14_21
No TF enriched


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_14_21 GO:0071222 cellular response to lipopolysaccharide 5/39 228/18986 9.8652820460545e-05 0.0171219252961012 0.013215907399103 CASP1/CD14/IRAK3/LY96/TSPO 5
MeSH_gene2pubmed B_14_21 D053473 Nod2 Signaling Adaptor Protein 4/40 160/26076 0.00010503047092499 0.0073598254891454 0.00522318816864972 CASP1/CD14/IRAK3/LY96 4
GO B_14_21 GO:0002237 response to molecule of bacterial origin 6/39 375/18986 0.00010726134022405 0.0171219252961012 0.013215907399103 CASP1/CD14/IRAK3/LY96/MAPKAPK3/TSPO 6
MeSH_gene2pubmed B_14_21 D000119 Acetylmuramyl-Alanyl-Isoglutamine 3/40 60/26076 0.0001076922308298 0.0073598254891454 0.00522318816864972 CASP1/IRAK3/LY96 3
MeSH_gene2pubmed B_14_21 D018805 Sepsis 5/40 312/26076 0.00011085126616044 0.0073598254891454 0.00522318816864972 CD14/FCGR3A/IRAK3/LY96/S100A12 5
MeSH_gene2pubmed B_14_21 D045604 Extracellular Fluid 4/40 163/26076 0.00011283749312603 0.0073598254891454 0.00522318816864972 CASP1/LY96/SERPINA1/TSPO 4
MeSH_gene2pubmed B_14_21 D053245 RANK Ligand 5/40 317/26076 0.00011941409924733 0.00751998167538412 0.00533684927356747 IL17RA/SPI1/TBXAS1/TCIRG1/ZFAND5 5
MeSH_gene2pubmed B_14_21 D016723 Bone Remodeling 4/40 166/26076 0.00012105758158916 0.00751998167538412 0.00533684927356747 IL17RA/SPI1/TBXAS1/TCIRG1 4
GO B_14_21 GO:0045089 positive regulation of innate immune response 6/39 387/18986 0.00012742543661782 0.0171219252961012 0.013215907399103 CASP1/CD14/IRAK3/LY96/MAPKAPK3/SPI1 6
GO B_14_21 GO:0071219 cellular response to molecule of bacterial origin 5/39 242/18986 0.00013048037905581 0.0171219252961012 0.013215907399103 CASP1/CD14/IRAK3/LY96/TSPO 5