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Selected Module: B_14_21


Module Info

Module_Name B_14_21
Cell_Type B
Name B_14_21: Immunologic Factors
Meta_Module B_10
Gene_Number 40

Genes:

AP2A1, ASAH1, CASP1, CD14, CFD, CNIH4, CPPED1, DUSP6, FCGR3A, FGL2, GABARAP, GLUL, GNS, GRINA, IFITM3, IL17RA, IRAK3, ITPK1, LEPROT, LY96, MAPKAPK3, MBOAT7, NAPRT, NEAT1, PICALM, PTTG1IP, RHOC, RNF144B, S100A12, SERPINA1, SH2B3, SLC7A7, SPI1, TBXAS1, TCIRG1, TSPO, VCAN, ZDHHC7, ZFAND5, ZYX


UMAP Visualizations


UMAP for B_14_21

UMAP for B_14_21


Word Cloud

Enriched TF

Wordcloud for B_14_21
No TF enriched


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_14_21 GO:0050729 positive regulation of inflammatory response 4/39 162/18986 0.00033286094380035 0.0204441390989078 0.0157802259099373 CASP1/IL17RA/NEAT1/S100A12 4
GO B_14_21 GO:0002758 innate immune response-activating signaling pathway 5/39 297/18986 0.00033723395607659 0.0204441390989078 0.0157802259099373 CASP1/CD14/IRAK3/LY96/MAPKAPK3 5
MeSH_gene2pubmed B_14_21 D015212 Inflammatory Bowel Diseases 5/40 397/26076 0.00033854786430206 0.0135426782090263 0.00961109155339906 CD14/FCGR3A/S100A12/SERPINA1/VCAN 5
MeSH_gene2pubmed B_14_21 D009283 Naphthol AS D Esterase 2/40 18/26076 0.00034562157657983 0.0135426782090263 0.00961109155339906 SPI1/TCIRG1 2
GO B_14_21 GO:0050832 defense response to fungus 3/39 67/18986 0.00035051338005664 0.0204441390989078 0.0157802259099373 IL17RA/S100A12/SPI1 3
MeSH_gene2pubmed B_14_21 D011550 Pseudomonas aeruginosa 4/40 220/26076 0.00035506529797537 0.0135426782090263 0.00961109155339906 ASAH1/LY96/SERPINA1/SPI1 4
MeSH_gene2pubmed B_14_21 D016167 Integrin alphaXbeta2 3/40 90/26076 0.0003581253427609 0.0135426782090263 0.00961109155339906 CD14/IL17RA/SPI1 3
MeSH_gene2pubmed B_14_21 D007156 Immunologic Memory 5/40 403/26076 0.00036261149805904 0.0135426782090263 0.00961109155339906 FCGR3A/FGL2/IL17RA/SPI1/TCIRG1 5
GO B_14_21 GO:0045088 regulation of innate immune response 6/39 470/18986 0.00036352829896449 0.0204441390989078 0.0157802259099373 CASP1/CD14/IRAK3/LY96/MAPKAPK3/SPI1 6
MeSH_gene2pubmed B_14_21 D011014 Pneumonia 4/40 222/26076 0.0003674350317912 0.0135426782090263 0.00961109155339906 FCGR3A/LY96/S100A12/SERPINA1 4