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Selected Module: B_14_21
Module Info
| Module_Name | B_14_21 |
| Cell_Type | B |
| Name | B_14_21: Immunologic Factors |
| Meta_Module | B_10 |
| Gene_Number | 40 |
Genes:
AP2A1, ASAH1, CASP1, CD14, CFD, CNIH4, CPPED1, DUSP6, FCGR3A, FGL2, GABARAP, GLUL, GNS, GRINA, IFITM3, IL17RA, IRAK3, ITPK1, LEPROT, LY96, MAPKAPK3, MBOAT7, NAPRT, NEAT1, PICALM, PTTG1IP, RHOC, RNF144B, S100A12, SERPINA1, SH2B3, SLC7A7, SPI1, TBXAS1, TCIRG1, TSPO, VCAN, ZDHHC7, ZFAND5, ZYX
UMAP Visualizations
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Enriched TF
No TF enriched
Functional Enrichment Results
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enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_14_21 | D007155 | Immunologic Factors | 7/40 | 326/26076 | 5.85629117478369e-07 | 0.00152790636750107 | 0.0010843385448889 | CASP1/CD14/FCGR3A/LY96/S100A12/SERPINA1/TCIRG1 | 7 |
| reactome | B_14_21 | R-HSA-6798695 | Neutrophil degranulation | 10/33 | 479/11146 | 7.4212239155804e-07 | 4.67728125029728e-05 | 3.45469247589405e-05 | ASAH1/CD14/CFD/CPPED1/FGL2/GNS/NAPRT/S100A12/SERPINA1/TCIRG1 | 10 |
| reactome | B_14_21 | R-HSA-166058 | MyD88:MAL(TIRAP) cascade initiated on plasma membrane | 6/33 | 113/11146 | 8.41953724552315e-07 | 4.67728125029728e-05 | 3.45469247589405e-05 | CD14/DUSP6/IRAK3/LY96/MAPKAPK3/S100A12 | 6 |
| reactome | B_14_21 | R-HSA-168188 | Toll Like Receptor TLR6:TLR2 Cascade | 6/33 | 113/11146 | 8.41953724552315e-07 | 4.67728125029728e-05 | 3.45469247589405e-05 | CD14/DUSP6/IRAK3/LY96/MAPKAPK3/S100A12 | 6 |
| reactome | B_14_21 | R-HSA-168179 | Toll Like Receptor TLR1:TLR2 Cascade | 6/33 | 116/11146 | 9.82622111406991e-07 | 4.67728125029728e-05 | 3.45469247589405e-05 | CD14/DUSP6/IRAK3/LY96/MAPKAPK3/S100A12 | 6 |
| reactome | B_14_21 | R-HSA-181438 | Toll Like Receptor 2 (TLR2) Cascade | 6/33 | 116/11146 | 9.82622111406991e-07 | 4.67728125029728e-05 | 3.45469247589405e-05 | CD14/DUSP6/IRAK3/LY96/MAPKAPK3/S100A12 | 6 |
| GO | B_14_21 | GO:0101002 | ficolin-1-rich granule | 6/40 | 185/19960 | 1.72673403248405e-06 | 0.00023656256245031 | 0.00016903817370633 | ASAH1/CFD/FGL2/GNS/SERPINA1/TCIRG1 | 6 |
| MeSH_gene2pubmed | B_14_21 | D010457 | Peptidoglycan | 5/40 | 134/26076 | 1.89332357443158e-06 | 0.00157354784250006 | 0.00111672980369878 | CASP1/CD14/IRAK3/LY96/SPI1 | 5 |
| MeSH_gene2pubmed | B_14_21 | D005340 | Fibrinogen | 7/40 | 412/26076 | 2.77755677329849e-06 | 0.00157354784250006 | 0.00111672980369878 | CD14/CFD/FCGR3A/FGL2/SERPINA1/SPI1/ZYX | 7 |
| reactome | B_14_21 | R-HSA-166016 | Toll Like Receptor 4 (TLR4) Cascade | 6/33 | 147/11146 | 3.92297251685472e-06 | 0.00015561124316857 | 0.00011493621233591 | CD14/DUSP6/IRAK3/LY96/MAPKAPK3/S100A12 | 6 |