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Selected Module: B_14_19


Module Info

Module_Name B_14_19
Cell_Type B
Name B_14_19: Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Meta_Module B_5
Gene_Number 30

Genes:

ARHGAP18, AVEN, CAPN10, CBX6, CDC23, CNOT3, DHX16, DYNLT1, FADD, GLA, GNPNAT1, IL12RB1, MBIP, MPND, MPV17L2, NUDT18, PLAAT3, PNPLA4, PRADC1, RAD17, RAP2A, RASGRP3, REC8, RIOX2, SLC35F2, SQOR, STN1, SUCLA2, UBE2E1, ZNF576


UMAP Visualizations


UMAP for B_14_19

UMAP for B_14_19


Word Cloud

Enriched TF

Wordcloud for B_14_19
TF p.adjust Genes
PHF21A 0.0436287600624631 CAPN10/MPV17L2/SLC35F2/ZNF576


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
reactome B_14_19 R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 2/24 19/11146 0.00074305419568101 0.0262200854747609 0.0194415728114745 CDC23/UBE2E1 2
reactome B_14_19 R-HSA-176412 Phosphorylation of the APC/C 2/24 19/11146 0.00074305419568101 0.0262200854747609 0.0194415728114745 CDC23/UBE2E1 2
reactome B_14_19 R-HSA-9687136 Aberrant regulation of mitotic exit in cancer due to RB1 defects 2/24 19/11146 0.00074305419568101 0.0262200854747609 0.0194415728114745 CDC23/UBE2E1 2
reactome B_14_19 R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 2/24 20/11146 0.00082453098977235 0.0262200854747609 0.0194415728114745 CDC23/UBE2E1 2
reactome B_14_19 R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 2/24 20/11146 0.00082453098977235 0.0262200854747609 0.0194415728114745 CDC23/UBE2E1 2
reactome B_14_19 R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 2/24 23/11146 0.00109360691757483 0.0289805833157331 0.0214884166260318 CDC23/UBE2E1 2
reactome B_14_19 R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 2/24 25/11146 0.00129336318939702 0.0293778210163037 0.0217829589793182 CDC23/UBE2E1 2
reactome B_14_19 R-HSA-9687139 Aberrant regulation of mitotic cell cycle due to RB1 defects 2/24 35/11146 0.00253169974719039 0.0473737316618463 0.0351265008018986 CDC23/UBE2E1 2
reactome B_14_19 R-HSA-9675126 Diseases of mitotic cell cycle 2/24 37/11146 0.00282637216135993 0.0473737316618463 0.0351265008018986 CDC23/UBE2E1 2
reactome B_14_19 R-HSA-8853884 Transcriptional Regulation by VENTX 2/24 38/11146 0.00297947997873247 0.0473737316618463 0.0351265008018986 CDC23/UBE2E1 2