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Selected Module: B_14_16
Module Info
| Module_Name | B_14_16 |
| Cell_Type | B |
| Name | B_14_16: protein-folding chaperone binding |
| Meta_Module | B_23 |
| Gene_Number | 39 |
Genes:
ACTL6A, ALYREF, ANP32A, ARMC6, BCAT2, BDH1, CDKN2AIPNL, E2F4, GET4, GPN3, KARS1, KPNB1, KRT10, LSR, LYRM4, MRPL38, MSMO1, NOC4L, PAGR1, PGRMC1, POLE4, POLR1H, POLR2C, PRPF31, PSMA2, RGS10, RNF7, SAP18, SLC25A17, SLC25A19, SOD1, SRP14, STUB1, THOP1, TIMM21, TIMM22, TSFM, UBE2V1, UBL4A
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| EPC1 | 0.00389777022785161 | ANP32A/GPN3/KPNB1/NOC4L/TIMM22/TSFM |
| ZNF622 | 0.0160536179731115 | ACTL6A/ANP32A/KPNB1 |
| NPAT | 0.0471042895686419 | ARMC6/PAGR1/PRPF31/UBE2V1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_14_16 | GO:0051087 | protein-folding chaperone binding | 5/37 | 134/18737 | 6.29544743761175e-06 | 0.00071768100788774 | 0.0005367697288911 | GET4/SLC25A17/SOD1/STUB1/UBL4A | 5 |
| KEGG | B_14_16 | hsa03060 | Protein export | 3/25 | 31/8541 | 9.43460779638592e-05 | 0.00424557350837367 | 0.00387315477956896 | GET4/SRP14/UBL4A | 3 |
| GO | B_14_16 | GO:0045047 | protein targeting to ER | 3/37 | 46/18986 | 9.76191340600857e-05 | 0.0403687247013379 | 0.0349712718073048 | GET4/SRP14/UBL4A | 3 |
| GO | B_14_16 | GO:0005048 | signal sequence binding | 3/37 | 48/18737 | 0.00011531777919718 | 0.0065731134142397 | 0.00491617900788011 | KPNB1/SRP14/TIMM22 | 3 |
| GO | B_14_16 | GO:0072599 | establishment of protein localization to endoplasmic reticulum | 3/37 | 50/18986 | 0.0001253687102526 | 0.0403687247013379 | 0.0349712718073048 | GET4/SRP14/UBL4A | 3 |
| GO | B_14_16 | GO:0016779 | nucleotidyltransferase activity | 4/37 | 146/18737 | 0.00019130346112241 | 0.00726953152265168 | 0.0054370457371633 | KARS1/POLE4/POLR1H/POLR2C | 4 |
| GO | B_14_16 | GO:0072379 | ER membrane insertion complex | 2/38 | 14/19960 | 0.00031656327477095 | 0.0242733223418346 | 0.0156544035859126 | GET4/UBL4A | 2 |
| GO | B_14_16 | GO:0098798 | mitochondrial protein-containing complex | 4/38 | 178/19960 | 0.00035616956405866 | 0.0242733223418346 | 0.0156544035859126 | LYRM4/MRPL38/TIMM21/TIMM22 | 4 |
| GO | B_14_16 | GO:0005758 | mitochondrial intermembrane space | 3/38 | 87/19960 | 0.00060428041462469 | 0.0242733223418346 | 0.0156544035859126 | SOD1/THOP1/TIMM21 | 3 |
| GO | B_14_16 | GO:0035145 | exon-exon junction complex | 2/38 | 21/19960 | 0.00072441378503235 | 0.0242733223418346 | 0.0156544035859126 | ALYREF/SAP18 | 2 |