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Selected Module: B_14_14


Module Info

Module_Name B_14_14
Cell_Type B
Name B_14_14: protein methylation
Meta_Module B_25
Gene_Number 41

Genes:

ALAS1, ARV1, ATP6V1C1, ATP6V1D, BECN1, C8orf76, CCDC43, CPSF2, CPT1A, CYSTM1, DCTN5, DPH3, EEF2KMT, EIF4EBP2, FAM98A, FBXO22, GEMIN6, GSKIP, IFT52, INTS13, INTS5, MAPRE1, MFAP1, NIF3L1, PEPD, PRMT5, RAB35, RBBP8, RBM28, RMDN3, RPL7L1, SCFD2, SFXN1, SOD2, TFB2M, TMUB1, TOMM70, UGDH, WDR54, YRDC, ZMPSTE24


UMAP Visualizations


UMAP for B_14_14

UMAP for B_14_14


Word Cloud

Enriched TF

Wordcloud for B_14_14
TF p.adjust Genes
WCTCNATGGY 0.00179946365423661 ATP6V1D/DPH3/TFB2M/WDR54
NRF2 0.00645358360822982 ATP6V1D/DCTN5/FBXO22/INTS13/TOMM70
ZNF704 0.0138761467393069 CPSF2/DPH3/PEPD
WDHD1 0.0148048915103258 INTS5/RBBP8/RBM28/ZMPSTE24
NRF1 0.0310811496728278 ATP6V1D/DCTN5/INTS13/RBBP8
GCGNNANTTCC 0.0365055436056954 FBXO22/GSKIP/YRDC


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
reactome B_14_14 R-HSA-1852241 Organelle biogenesis and maintenance 5/26 298/11146 0.00054753701813084 0.0457193410139256 0.0397684781589772 ALAS1/IFT52/MAPRE1/SOD2/TFB2M 5
GO B_14_14 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain 2/40 19/19960 0.00065531948925892 0.0209336758591611 0.0153154179484718 ATP6V1C1/ATP6V1D 2
GO B_14_14 GO:0032039 integrator complex 2/40 21/19960 0.00080274090589016 0.0209336758591611 0.0153154179484718 INTS13/INTS5 2
GO B_14_14 GO:0008168 methyltransferase activity 4/40 205/18737 0.00093423320590602 0.0216469822245802 0.0180391518538168 EEF2KMT/FAM98A/PRMT5/TFB2M 4
GO B_14_14 GO:0005741 mitochondrial outer membrane 4/40 223/19960 0.00101113125449829 0.0209336758591611 0.0153154179484718 BECN1/CPT1A/RMDN3/TOMM70 4
GO B_14_14 GO:0008276 protein methyltransferase activity 3/40 95/18737 0.00108890118134519 0.0216469822245802 0.0180391518538168 EEF2KMT/FAM98A/PRMT5 3
GO B_14_14 GO:0016741 transferase activity, transferring one-carbon groups 4/40 216/18737 0.00113395085317355 0.0216469822245802 0.0180391518538168 EEF2KMT/FAM98A/PRMT5/TFB2M 4
GO B_14_14 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/40 24/18737 0.00119054586155937 0.0216469822245802 0.0180391518538168 ATP6V1C1/ATP6V1D 2
GO B_14_14 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/40 24/18737 0.00119054586155937 0.0216469822245802 0.0180391518538168 ATP6V1C1/ATP6V1D 2
GO B_14_14 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/40 24/18737 0.00119054586155937 0.0216469822245802 0.0180391518538168 ATP6V1C1/ATP6V1D 2