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Selected Module: B_13_5
Module Info
| Module_Name | B_13_5 |
| Cell_Type | B |
| Name | B_13_5: Spliceosomes |
| Meta_Module | B_9 |
| Gene_Number | 49 |
Genes:
ACAT2, ANP32E, ARHGDIA, BCCIP, C8orf33, CBX5, CENPH, CENPM, CKAP2, CKS1B, DNMT1, DYNC2I2, EIF1AX, EIF4A1, H2AZ2, H4C3, HMGB1, HMGN1, HNRNPA2B1, HNRNPD, HNRNPR, HSPH1, KIF20B, LSM7, MCMBP, MYBL2, NCAPH2, POLR3K, PPIH, PTBP1, PTGES3, PUM3, RBM14, RBM8A, RFC2, SAE1, SMC2, SMC3, SNRPD1, SQLE, SRSF2, SSB, TACC3, TFAM, TUBB, TUBB4B, USP1, YWHAQ, ZPR1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| SMARCA1 | 0.0199409767136744 | H4C3/HSPH1/TUBB4B |
| PSMB5 | 0.0227685346920554 | H4C3/HNRNPA2B1/SRSF2/TUBB4B |
| FOXQ1 | 0.0227685346920554 | BCCIP/SMC3 |
| TTCNRGNNNNTTC | 0.0265082529313917 | EIF4A1/HNRNPA2B1/HSPH1 |
| NR1I2 | 0.0322224511595727 | ACAT2/CKAP2/H2AZ2/MCMBP |
| E2F | 0.0382448503015431 | ANP32E/HNRNPR/USP1 |
| YBX3 | 0.0446227913085866 | C8orf33/NCAPH2 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_13_5 | D017381 | Spliceosomes | 12/49 | 422/26076 | 1.48467769526857e-11 | 2.4749577180127e-08 | 1.98790529303328e-08 | CBX5/HNRNPA2B1/HNRNPD/HNRNPR/LSM7/PPIH/PTBP1/RBM14/RBM8A/SNRPD1/SRSF2/ZPR1 | 12 |
| MeSH_gene2pubmed | B_13_5 | D028884 | Karyopherins | 11/49 | 377/26076 | 8.89040966520158e-11 | 7.41015645594551e-08 | 5.95189531270337e-08 | CKS1B/DNMT1/EIF1AX/EIF4A1/HMGB1/HNRNPD/PTBP1/RBM8A/SRSF2/SSB/YWHAQ | 11 |
| hallmark | B_13_5 | HALLMARK_E2F_TARGETS | HALLMARK_E2F_TARGETS | 13/33 | 200/4384 | 6.45646453681164e-10 | 9.0390503515363e-09 | 7.4759063057819e-09 | ANP32E/CBX5/CENPM/CKS1B/DNMT1/HNRNPD/MYBL2/RFC2/SMC3/SRSF2/TACC3/TUBB/USP1 | 13 |
| MeSH_gene2pubmed | B_13_5 | D034521 | Nuclear Matrix-Associated Proteins | 9/49 | 270/26076 | 1.71319108523184e-09 | 9.51963179693827e-07 | 7.64624231724527e-07 | HNRNPA2B1/HNRNPD/PTBP1/RBM14/RBM8A/SMC3/SNRPD1/SRSF2/TUBB | 9 |
| hallmark | B_13_5 | HALLMARK_MYC_TARGETS_V1 | HALLMARK_MYC_TARGETS_V1 | 12/33 | 200/4384 | 8.93494988743177e-09 | 6.25446492120224e-08 | 5.1728657243026e-08 | EIF1AX/EIF4A1/HNRNPA2B1/HNRNPD/HNRNPR/LSM7/PTGES3/SNRPD1/SRSF2/SSB/USP1/YWHAQ | 12 |
| MeSH_gene2pubmed | B_13_5 | D034441 | Heterogeneous-Nuclear Ribonucleoproteins | 10/49 | 450/26076 | 9.55093796746968e-09 | 3.98035339794299e-06 | 3.19705081437406e-06 | DNMT1/HMGB1/HNRNPA2B1/HNRNPD/HNRNPR/PTBP1/RBM8A/SNRPD1/SRSF2/SSB | 10 |
| MeSH_gene2pubmed | B_13_5 | D034641 | Heterogeneous-Nuclear Ribonucleoprotein K | 6/49 | 90/26076 | 1.77158245129002e-08 | 5.90645589260092e-06 | 4.74411132219138e-06 | DNMT1/HMGB1/HNRNPD/HNRNPR/PTBP1/SSB | 6 |
| reactome | B_13_5 | R-HSA-72163 | mRNA Splicing - Major Pathway | 9/41 | 207/11146 | 4.62501604718183e-08 | 1.18015006592039e-05 | 8.30425961717436e-06 | HNRNPA2B1/HNRNPD/HNRNPR/LSM7/PPIH/PTBP1/RBM8A/SNRPD1/SRSF2 | 9 |
| MeSH_gene2pubmed | B_13_5 | D034482 | Heterogeneous-Nuclear Ribonucleoprotein Group C | 5/49 | 54/26076 | 5.60472631650877e-08 | 1.55717979493669e-05 | 1.25073892536827e-05 | HNRNPA2B1/HNRNPD/HNRNPR/PTBP1/SSB | 5 |
| reactome | B_13_5 | R-HSA-72172 | mRNA Splicing | 9/41 | 215/11146 | 6.41385905391516e-08 | 1.18015006592039e-05 | 8.30425961717436e-06 | HNRNPA2B1/HNRNPD/HNRNPR/LSM7/PPIH/PTBP1/RBM8A/SNRPD1/SRSF2 | 9 |