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Selected Module: B_13_34
Module Info
| Module_Name | B_13_34 |
| Cell_Type | B |
| Name | B_13_34: protein sequestering activity |
| Meta_Module | B_12 |
| Gene_Number | 33 |
Genes:
AKIRIN1, ARIH2, BCAS2, BRD2, CDKN1A, CEBPG, CMTM6, GTF2B, IDS, INSIG1, KLHL18, KRAS, LINC00513, LMNA, MAPK1IP1L, MED31, MORF4L1, MTRF1L, NUP98, PIP5K1B, RBM27, RGS2, RNF139, SENP2, SQSTM1, TERF2IP, TIPARP, TP53BP1, VAMP3, YWHAZ, ZC3H15, ZFAND2A, ZNF335
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| BACH1 | 0.00016556973878803 | BRD2/CDKN1A/GTF2B/LMNA/RGS2/SQSTM1 |
| TGACGTCA | 0.00061684609226602 | AKIRIN1/NUP98/SENP2/YWHAZ/ZNF335 |
| AP1 | 0.00061684609226602 | CDKN1A/GTF2B/IDS/LMNA/YWHAZ |
| CREBP1CJUN | 0.00061684609226602 | AKIRIN1/NUP98/SENP2/YWHAZ/ZNF335 |
| AP1 | 0.00061684609226602 | BRD2/IDS/LMNA/RGS2/SQSTM1 |
| CREB | 0.00061684609226602 | AKIRIN1/NUP98/SENP2/YWHAZ/ZNF335 |
| AP1 | 0.00061684609226602 | CDKN1A/GTF2B/IDS/LMNA/SQSTM1 |
| GTTRYCATRR | 0.00184841475220384 | KLHL18/RNF139/TP53BP1/YWHAZ |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_13_34 | GO:0140311 | protein sequestering activity | 4/32 | 32/18737 | 2.43579779804588e-07 | 3.23961107140103e-05 | 2.41015782122435e-05 | CDKN1A/INSIG1/SQSTM1/YWHAZ | 4 |
| MeSH_gene2pubmed | B_13_34 | D022003 | Cell Nucleus Structures | 5/32 | 136/26076 | 6.44504688323279e-07 | 0.00205564814213871 | 0.00142665609864677 | GTF2B/LMNA/RBM27/SENP2/TP53BP1 | 5 |
| MeSH_gene2pubmed | B_13_34 | D014898 | Werner Syndrome | 4/32 | 67/26076 | 1.35566879610458e-06 | 0.00205564814213871 | 0.00142665609864677 | CDKN1A/IDS/LMNA/TP53BP1 | 4 |
| MeSH_gene2pubmed | B_13_34 | D035341 | Telomeric Repeat Binding Protein 2 | 4/32 | 73/26076 | 1.91520013242737e-06 | 0.00205564814213871 | 0.00142665609864677 | CDKN1A/GTF2B/TERF2IP/TP53BP1 | 4 |
| GO | B_13_34 | GO:0140313 | molecular sequestering activity | 4/32 | 54/18737 | 2.08652887970843e-06 | 0.00013875417050061 | 0.00010322827089083 | CDKN1A/INSIG1/SQSTM1/YWHAZ | 4 |
| MeSH_gene2pubmed | B_13_34 | D054325 | vpr Gene Products, Human Immunodeficiency Virus | 5/32 | 231/26076 | 8.65542945728856e-06 | 0.0066618392015857 | 0.00462343400620021 | CDKN1A/GTF2B/LMNA/NUP98/YWHAZ | 5 |
| MeSH_gene2pubmed | B_13_34 | D016336 | Gene Products, vpr | 5/32 | 245/26076 | 1.15050509354181e-05 | 0.0066618392015857 | 0.00462343400620021 | CDKN1A/GTF2B/LMNA/NUP98/YWHAZ | 5 |
| MeSH_gene2pubmed | B_13_34 | D013090 | Spermatocytes | 5/32 | 254/26076 | 1.36924648107699e-05 | 0.0066618392015857 | 0.00462343400620021 | BRD2/CDKN1A/LMNA/RNF139/TERF2IP | 5 |
| MeSH_gene2pubmed | B_13_34 | D008540 | Meiosis | 6/32 | 443/26076 | 1.4482259133882e-05 | 0.0066618392015857 | 0.00462343400620021 | BRD2/CDKN1A/MAPK1IP1L/RNF139/SQSTM1/TERF2IP | 6 |
| MeSH_gene2pubmed | B_13_34 | D019588 | Aging, Premature | 3/32 | 47/26076 | 2.62384578751065e-05 | 0.00918947471022353 | 0.00637765766910904 | CDKN1A/LMNA/TP53BP1 | 3 |