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Selected Module: B_13_31
Module Info
| Module_Name | B_13_31 |
| Cell_Type | B |
| Name | B_13_31: alpha-beta T cell differentiation |
| Meta_Module | B_16 |
| Gene_Number | 38 |
Genes:
AP1S3, BEX2, C6orf62, C9orf78, CFAP20, CGRRF1, DNAJB2, E2F5, EAF1, FEM1B, GGA1, HIPK3, IER5, IRS2, MAP9, MED19, MOAP1, MTCH1, MTMR9, NXT1, PDE12, PIM3, PRR7, PTGER4, PTS, RAD1, RAP2C, RELB, RIPK2, RRAGC, SNHG9, SOCS1, SVIP, TMEM38B, TOE1, TSPAN33, WTAP, ZNF655
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| CTGRYYYNATT | 0.0353403551586647 | MOAP1/SOCS1/TSPAN33 |
| RYTGCNNRGNAAC | 0.0353403551586647 | C6orf62/E2F5/MAP9 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_13_31 | GO:0046632 | alpha-beta T cell differentiation | 5/37 | 133/18986 | 5.69508892169071e-06 | 0.00552423625403999 | 0.00446614868069429 | PRR7/PTGER4/RELB/RIPK2/SOCS1 | 5 |
| GO | B_13_31 | GO:0046631 | alpha-beta T cell activation | 5/37 | 196/18986 | 3.71307226426855e-05 | 0.0146304996571966 | 0.0118282390066321 | PRR7/PTGER4/RELB/RIPK2/SOCS1 | 5 |
| GO | B_13_31 | GO:0043367 | CD4-positive, alpha-beta T cell differentiation | 4/37 | 102/18986 | 4.52489680119483e-05 | 0.0146304996571966 | 0.0118282390066321 | PTGER4/RELB/RIPK2/SOCS1 | 4 |
| GO | B_13_31 | GO:0035710 | CD4-positive, alpha-beta T cell activation | 4/37 | 129/18986 | 0.00011291054804528 | 0.0273808079009814 | 0.0221364100772991 | PTGER4/RELB/RIPK2/SOCS1 | 4 |
| hallmark | B_13_31 | HALLMARK_TNFA_SIGNALING_VIA_NFKB | HALLMARK_TNFA_SIGNALING_VIA_NFKB | 5/12 | 200/4384 | 0.00011455087451015 | 0.00194736486667256 | 0.00180869801858132 | IER5/IRS2/PTGER4/RELB/RIPK2 | 5 |
| GO | B_13_31 | GO:0008408 | 3'-5' exonuclease activity | 3/37 | 58/18737 | 0.00020295005349058 | 0.0104120056742556 | 0.00635065766654054 | PDE12/RAD1/TOE1 | 3 |
| GO | B_13_31 | GO:0016796 | exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 3/37 | 60/18737 | 0.0002244655504676 | 0.0104120056742556 | 0.00635065766654054 | PDE12/RAD1/TOE1 | 3 |
| GO | B_13_31 | GO:0004535 | poly(A)-specific ribonuclease activity | 2/37 | 13/18737 | 0.00029192539273613 | 0.0104120056742556 | 0.00635065766654054 | PDE12/TOE1 | 2 |
| WikiPathways | B_13_31 | WP3935 | Leptin insulin signaling overlap | 2/17 | 17/8836 | 0.00046587571354948 | 0.038667684224607 | 0.0313853112285966 | IRS2/SOCS1 | 2 |
| GO | B_13_31 | GO:0004527 | exonuclease activity | 3/37 | 84/18737 | 0.00060497978063112 | 0.0161832091318826 | 0.00987072273661307 | PDE12/RAD1/TOE1 | 3 |