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Selected Module: B_13_13
Module Info
| Module_Name | B_13_13 |
| Cell_Type | B |
| Name | B_13_13: Immunologic Deficiency Syndromes |
| Meta_Module | B_11 |
| Gene_Number | 109 |
Genes:
ALOX5, ANAPC16, ARFGAP2, ARHGAP17, ARL11, ATP6V1H, BCAP29, C19orf25, C1orf162, CAMK2G, CCDC18, CCDC191, CCDC28A, CCDC6, CCNB1IP1, CCNDBP1, CD40, CD72, CEBPZOS, CEP164, CHI3L2, CLASRP, CLEC17A, CLNS1A, CNFN, CYBB, CYP2R1, DEGS1, DLGAP4, DPH5, EAPP, EHMT2, ELMO1, ELOVL5, ENDOD1, EXOC6, FCHO1, GCA, GCNT1, GGA3, GMCL1, HDAC9, HEATR6, IFI16, IFNGR1, IFNGR2, IP6K2, IRAK4, IRF2, JADE2, KIAA0040, KMT2E-AS1, KRI1, LAIR1, LDAF1, LHPP, LRCH1, MAX, MED30, MGME1, MITD1, MRFAP1, MYO1E, NADSYN1, NOC3L, NSMCE1, NT5C3A, NT5E, NUMA1, OARD1, PATL2, PHF11, PHYKPL, PNRC2, POLH, PPP1R21, PPP1R9B, PSIP1, RALB, RAP1GDS1, RFX5, RHOH, RINL, RPP38, RRAGB, RRAS2, SKAP2, SLC25A13, SNHG30, SNHG7, SPART, STAT6, STK10, TAGAP, TGS1, TRMT1, TRMT2B, UGP2, UIMC1, UPF3B, UTP18, UTP6, UXS1, VCPKMT, WSB1, ZNF143, ZNF33B, ZNF672, ZNF84
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| GCCATNTTG | 0.00445631210720724 | CCDC6/CCNB1IP1/EXOC6/MGME1/OARD1/PNRC2/PPP1R21/UPF3B/WSB1/ZNF143 |
| ETS2 | 0.00445631210720724 | DLGAP4/ELMO1/IRAK4/NT5C3A/PPP1R9B/PSIP1/TRMT2B/ZNF143 |
| PU1 | 0.00798073544313662 | C1orf162/ELMO1/ELOVL5/IRAK4/LAIR1/RINL/STAT6 |
| NFY | 0.0120760364985272 | ELMO1/GCA/MYO1E/PNRC2/RFX5/SLC25A13/UGP2 |
| SMTTTTGT | 0.0213521640063999 | CAMK2G/IP6K2/JADE2/MRFAP1/PNRC2/RRAS2/VCPKMT/ZNF143 |
| ZNF302 | 0.0213521640063999 | SNHG30/STAT6 |
| YY1 | 0.0341549583423891 | CCDC6/CCNB1IP1/EXOC6/MGME1/PNRC2/UPF3B |
| ETS | 0.0341549583423891 | ELMO1/FCHO1/IRAK4/PPP1R9B/RINL/TRMT2B |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_13_13 | D007153 | Immunologic Deficiency Syndromes | 8/106 | 218/26076 | 3.13460655099284e-06 | 0.00992729894699432 | 0.00877689834277995 | CD40/CD72/CYBB/IFNGR1/IRAK4/IRF2/NT5E/RFX5 | 8 |
| onek1k | B_13_13 | B naive | B naive | 10/53 | 196/6471 | 3.23812274429312e-06 | 2.26668592100519e-05 | 1.36342010286026e-05 | CCDC191/CD40/CD72/CLEC17A/CNFN/ELOVL5/HDAC9/RHOH/RRAS2/SNHG7 | 10 |
| onek1k | B_13_13 | B intermediate | B intermediate | 10/53 | 233/6471 | 1.5079351513911e-05 | 5.27777302986884e-05 | 3.1746003187181e-05 | ALOX5/CCDC191/CD40/CD72/CLEC17A/CNFN/IFNGR2/KIAA0040/RHOH/RRAS2 | 10 |
| MeSH_gene2pubmed | B_13_13 | D017471 | Receptors, Interferon | 8/106 | 273/26076 | 1.62017094040265e-05 | 0.017582301537316 | 0.0155448197993321 | CYBB/IFI16/IFNGR1/IFNGR2/IRAK4/IRF2/PNRC2/STAT6 | 8 |
| MeSH_gene2pubmed | B_13_13 | D007073 | Immunoglobulin E | 10/106 | 482/26076 | 2.77306742372636e-05 | 0.017582301537316 | 0.0155448197993321 | ALOX5/CD40/CD72/CYP2R1/IFNGR1/IFNGR2/LAIR1/PHF11/PSIP1/STAT6 | 10 |
| MeSH_gene2pubmed | B_13_13 | D006969 | Hypersensitivity, Immediate | 7/106 | 214/26076 | 2.7848435764585e-05 | 0.017582301537316 | 0.0155448197993321 | CD40/IFNGR1/IFNGR2/IRF2/PHF11/PSIP1/STAT6 | 7 |
| MeSH_gene2pubmed | B_13_13 | D000917 | Antibody Formation | 10/106 | 484/26076 | 2.87207934550721e-05 | 0.017582301537316 | 0.0155448197993321 | CD40/CD72/GCNT1/IFNGR1/IFNGR2/IRAK4/IRF2/LAIR1/NUMA1/STAT6 | 10 |
| MeSH_gene2pubmed | B_13_13 | D007156 | Immunologic Memory | 9/106 | 403/26076 | 4.03362147915119e-05 | 0.017582301537316 | 0.0155448197993321 | CAMK2G/CD40/CD72/GCNT1/IFNGR1/IFNGR2/LAIR1/POLH/STAT6 | 9 |
| MeSH_gene2pubmed | B_13_13 | D017578 | Immunoglobulin Class Switching | 6/106 | 155/26076 | 4.18508691596029e-05 | 0.017582301537316 | 0.0155448197993321 | CD40/CD72/GCNT1/LAIR1/POLH/STAT6 | 6 |
| MeSH_gene2pubmed | B_13_13 | D010950 | Plasma Cells | 8/106 | 317/26076 | 4.69110886897349e-05 | 0.017582301537316 | 0.0155448197993321 | CD40/CD72/GCNT1/IFNGR1/IRAK4/MAX/POLH/STAT6 | 8 |