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Selected Module: B_13_10
Module Info
| Module_Name | B_13_10 |
| Cell_Type | B |
| Name | B_13_10: Intercellular Junctions |
| Meta_Module | B_6 |
| Gene_Number | 74 |
Genes:
AGFG1, ANGEL2, ASAP1, ATR, BLTP3B, CDK11B, CERT1, CLSTN1, CMIP, CUL2, DOCK2, EEA1, EFR3A, EPS15, ERCC6L2, EXOC1, FNBP1, FXR1, G2E3, GABPB2, GALNT10, GGA2, GNB1, GSK3B, HTT, IPO7, KDM6A, KIAA0586, LRPPRC, MAP4, MARK2, MED17, MLH3, MPRIP, MYO9B, NCBP3, PDS5A, PHF6, PI4KA, PIP4K2A, PPIP5K2, PPP1R12A, PTEN, PTPN11, PTPN2, PTPRA, RBM19, RO60, ROCK2, RPS6KA3, SEPTIN7, SH3KBP1, SLC25A32, SMARCC1, SNRK, SOS2, STX17, TBL1XR1, TENT4B, TGOLN2, TMOD3, TNK2, TPR, UBR4, UBXN2A, VEZT, WDR20, WNK1, XIST, ZBTB40, ZC3H8, ZDHHC17, ZMYM4, ZMYND11
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| ETF | 0.00814695694547425 | CLSTN1/CUL2/GNB1/RO60/UBR4 |
| NFMUE1 | 0.0104026073134015 | CERT1/CLSTN1/GABPB2/KDM6A/RBM19/SEPTIN7 |
| RRAGTTGT | 0.0104026073134015 | CERT1/EPS15/IPO7/KDM6A/RPS6KA3/TMOD3 |
| RRCCGTTA | 0.0110610281088081 | FXR1/KIAA0586/UBR4/ZMYM4 |
| E2F | 0.0117162801242734 | CLSTN1/GNB1/PIP4K2A/TPR/ZMYM4 |
| E4BP4 | 0.0263722148756448 | CLSTN1/FNBP1/KDM6A/MAP4/RPS6KA3 |
| NPM1 | 0.0288762278591829 | ERCC6L2/NCBP3/PPP1R12A/RO60/SEPTIN7/TGOLN2 |
| ZIC2 | 0.0341299648703405 | FNBP1/KDM6A/MAP4/PHF6/ZMYND11 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_13_10 | GO:0006406 | mRNA export from nucleus | 4/71 | 74/18986 | 0.00016955631650428 | 0.0124129353374179 | 0.0101808156708056 | AGFG1/NCBP3/TPR/WNK1 | 4 |
| MeSH_gene2pubmed | B_13_10 | D021601 | trans-Golgi Network | 6/74 | 290/26076 | 0.0001765599832737 | 0.0126259171017644 | 0.00998858942327845 | CERT1/EPS15/GGA2/GNB1/PI4KA/TGOLN2 | 6 |
| MeSH_gene2pubmed | B_13_10 | D008670 | Metals | 7/74 | 418/26076 | 0.00018477035766768 | 0.0129377744191891 | 0.0102353053392229 | ATR/DOCK2/FNBP1/MAP4/PPP1R12A/SH3KBP1/SMARCC1 | 7 |
| MeSH_gene2pubmed | B_13_10 | D019859 | Proto-Oncogene Proteins c-met | 6/74 | 297/26076 | 0.00020082045497699 | 0.0137217285035462 | 0.010855505472982 | ATR/CUL2/PTEN/PTPN11/SH3KBP1/TPR | 6 |
| GO | B_13_10 | GO:0007163 | establishment or maintenance of cell polarity | 6/71 | 227/18986 | 0.00020482889594327 | 0.014395374806893 | 0.0118067687808984 | DOCK2/GSK3B/HTT/MAP4/MARK2/ROCK2 | 6 |
| MeSH_gene2pubmed | B_13_10 | D000205 | D000205 | 4/74 | 102/26076 | 0.00020576740597921 | 0.0137217285035462 | 0.010855505472982 | MYO9B/PPP1R12A/PTEN/ROCK2 | 4 |
| MeSH_gene2pubmed | B_13_10 | D012492 | Salts | 6/74 | 299/26076 | 0.00020821426768249 | 0.0137217285035462 | 0.010855505472982 | DOCK2/FNBP1/MAP4/PPP1R12A/SH3KBP1/SMARCC1 | 6 |
| GO | B_13_10 | GO:0006470 | protein dephosphorylation | 5/71 | 146/18986 | 0.0002173657715653 | 0.0146889100246249 | 0.0120475198895914 | PPP1R12A/PTEN/PTPN11/PTPN2/PTPRA | 5 |
| MeSH_gene2pubmed | B_13_10 | D015682 | Retroviridae Proteins, Oncogenic | 6/74 | 307/26076 | 0.0002399669247792 | 0.0155101698881325 | 0.0122703735221105 | EPS15/PTEN/PTPN11/SH3KBP1/TNK2/TPR | 6 |
| MeSH_gene2pubmed | B_13_10 | D051377 | Actin-Related Protein 2 | 4/74 | 107/26076 | 0.00024722436148505 | 0.015677756206628 | 0.0124029540637788 | EPS15/SH3KBP1/TGOLN2/TMOD3 | 4 |