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Selected Module: B_13_10
Module Info
| Module_Name | B_13_10 |
| Cell_Type | B |
| Name | B_13_10: Intercellular Junctions |
| Meta_Module | B_6 |
| Gene_Number | 74 |
Genes:
AGFG1, ANGEL2, ASAP1, ATR, BLTP3B, CDK11B, CERT1, CLSTN1, CMIP, CUL2, DOCK2, EEA1, EFR3A, EPS15, ERCC6L2, EXOC1, FNBP1, FXR1, G2E3, GABPB2, GALNT10, GGA2, GNB1, GSK3B, HTT, IPO7, KDM6A, KIAA0586, LRPPRC, MAP4, MARK2, MED17, MLH3, MPRIP, MYO9B, NCBP3, PDS5A, PHF6, PI4KA, PIP4K2A, PPIP5K2, PPP1R12A, PTEN, PTPN11, PTPN2, PTPRA, RBM19, RO60, ROCK2, RPS6KA3, SEPTIN7, SH3KBP1, SLC25A32, SMARCC1, SNRK, SOS2, STX17, TBL1XR1, TENT4B, TGOLN2, TMOD3, TNK2, TPR, UBR4, UBXN2A, VEZT, WDR20, WNK1, XIST, ZBTB40, ZC3H8, ZDHHC17, ZMYM4, ZMYND11
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| ETF | 0.00814695694547425 | CLSTN1/CUL2/GNB1/RO60/UBR4 |
| NFMUE1 | 0.0104026073134015 | CERT1/CLSTN1/GABPB2/KDM6A/RBM19/SEPTIN7 |
| RRAGTTGT | 0.0104026073134015 | CERT1/EPS15/IPO7/KDM6A/RPS6KA3/TMOD3 |
| RRCCGTTA | 0.0110610281088081 | FXR1/KIAA0586/UBR4/ZMYM4 |
| E2F | 0.0117162801242734 | CLSTN1/GNB1/PIP4K2A/TPR/ZMYM4 |
| E4BP4 | 0.0263722148756448 | CLSTN1/FNBP1/KDM6A/MAP4/RPS6KA3 |
| NPM1 | 0.0288762278591829 | ERCC6L2/NCBP3/PPP1R12A/RO60/SEPTIN7/TGOLN2 |
| ZIC2 | 0.0341299648703405 | FNBP1/KDM6A/MAP4/PHF6/ZMYND11 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_13_10 | D011972 | Receptor, Insulin | 7/74 | 385/26076 | 0.00011141105487047 | 0.00936131388549196 | 0.00740590327902181 | EPS15/PTEN/PTPN11/PTPN2/PTPRA/SH3KBP1/WNK1 | 7 |
| MeSH_gene2pubmed | B_13_10 | D003034 | Coated Pits, Cell-Membrane | 5/74 | 167/26076 | 0.00011440001385116 | 0.00937801089155492 | 0.00741911257992381 | AGFG1/EPS15/FNBP1/GGA2/SH3KBP1 | 5 |
| WikiPathways | B_13_10 | WP2038 | Microtubule cytoskeleton regulation | 4/47 | 48/8836 | 0.00011519473669271 | 0.0114042789325788 | 0.00891243489148898 | GSK3B/MARK2/PTEN/PTPRA | 4 |
| MeSH_gene2pubmed | B_13_10 | D033962 | Adaptor Protein Complex 2 | 5/74 | 170/26076 | 0.0001243639586558 | 0.00995207773909936 | 0.00787326715700684 | AGFG1/EEA1/EPS15/FXR1/TGOLN2 | 5 |
| MeSH_gene2pubmed | B_13_10 | D050719 | Crk-Associated Substrate Protein | 5/74 | 171/26076 | 0.00012782886910741 | 0.00999146114116298 | 0.00790442407259045 | PTEN/PTPN11/PTPRA/SH3KBP1/TNK2 | 5 |
| MeSH_gene2pubmed | B_13_10 | D025821 | D025821 | 5/74 | 174/26076 | 0.00013866908781998 | 0.0105924273673405 | 0.00837985923046148 | AGFG1/EPS15/HTT/PTEN/SH3KBP1 | 5 |
| MeSH_gene2pubmed | B_13_10 | D022001 | Focal Adhesions | 7/74 | 401/26076 | 0.00014323801929615 | 0.0106982885078748 | 0.0084636078770077 | ASAP1/GSK3B/PPP1R12A/PTEN/PTPN11/PTPRA/ROCK2 | 7 |
| GO | B_13_10 | GO:0048193 | Golgi vesicle transport | 7/71 | 308/18986 | 0.00015108207454587 | 0.0117273890009276 | 0.00961854569228041 | ASAP1/BLTP3B/EPS15/EXOC1/GGA2/HTT/STX17 | 7 |
| GO | B_13_10 | GO:0033081 | regulation of T cell differentiation in thymus | 3/71 | 28/18986 | 0.00015351732898197 | 0.0117273890009276 | 0.00961854569228041 | PTPN2/SOS2/ZC3H8 | 3 |
| MeSH_gene2pubmed | B_13_10 | D002402 | D002402 | 6/74 | 283/26076 | 0.00015467931751195 | 0.0113016779599492 | 0.00894096009233836 | CERT1/EEA1/FNBP1/GGA2/HTT/TGOLN2 | 6 |