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Selected Module: B_13_10
Module Info
| Module_Name | B_13_10 |
| Cell_Type | B |
| Name | B_13_10: Intercellular Junctions |
| Meta_Module | B_6 |
| Gene_Number | 74 |
Genes:
AGFG1, ANGEL2, ASAP1, ATR, BLTP3B, CDK11B, CERT1, CLSTN1, CMIP, CUL2, DOCK2, EEA1, EFR3A, EPS15, ERCC6L2, EXOC1, FNBP1, FXR1, G2E3, GABPB2, GALNT10, GGA2, GNB1, GSK3B, HTT, IPO7, KDM6A, KIAA0586, LRPPRC, MAP4, MARK2, MED17, MLH3, MPRIP, MYO9B, NCBP3, PDS5A, PHF6, PI4KA, PIP4K2A, PPIP5K2, PPP1R12A, PTEN, PTPN11, PTPN2, PTPRA, RBM19, RO60, ROCK2, RPS6KA3, SEPTIN7, SH3KBP1, SLC25A32, SMARCC1, SNRK, SOS2, STX17, TBL1XR1, TENT4B, TGOLN2, TMOD3, TNK2, TPR, UBR4, UBXN2A, VEZT, WDR20, WNK1, XIST, ZBTB40, ZC3H8, ZDHHC17, ZMYM4, ZMYND11
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| ETF | 0.00814695694547425 | CLSTN1/CUL2/GNB1/RO60/UBR4 |
| NFMUE1 | 0.0104026073134015 | CERT1/CLSTN1/GABPB2/KDM6A/RBM19/SEPTIN7 |
| RRAGTTGT | 0.0104026073134015 | CERT1/EPS15/IPO7/KDM6A/RPS6KA3/TMOD3 |
| RRCCGTTA | 0.0110610281088081 | FXR1/KIAA0586/UBR4/ZMYM4 |
| E2F | 0.0117162801242734 | CLSTN1/GNB1/PIP4K2A/TPR/ZMYM4 |
| E4BP4 | 0.0263722148756448 | CLSTN1/FNBP1/KDM6A/MAP4/RPS6KA3 |
| NPM1 | 0.0288762278591829 | ERCC6L2/NCBP3/PPP1R12A/RO60/SEPTIN7/TGOLN2 |
| ZIC2 | 0.0341299648703405 | FNBP1/KDM6A/MAP4/PHF6/ZMYND11 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_13_10 | GO:0032869 | cellular response to insulin stimulus | 7/71 | 213/18986 | 1.4667509527034e-05 | 0.00368154489128553 | 0.00301952188609166 | GSK3B/PIP4K2A/PTPN11/PTPN2/PTPRA/SMARCC1/SOS2 | 7 |
| MeSH_gene2pubmed | B_13_10 | D010769 | Phosphothreonine | 7/74 | 287/26076 | 1.74319477803369e-05 | 0.00292943882448562 | 0.002317531583849 | ATR/GSK3B/PPP1R12A/PTEN/PTPN11/RPS6KA3/WNK1 | 7 |
| MeSH_gene2pubmed | B_13_10 | D013572 | Synaptic Vesicles | 7/74 | 294/26076 | 2.03486800628458e-05 | 0.00325675779482022 | 0.00257647949066408 | EPS15/EXOC1/HTT/PIP4K2A/SEPTIN7/STX17/ZDHHC17 | 7 |
| GO | B_13_10 | GO:1902117 | positive regulation of organelle assembly | 5/71 | 89/18986 | 2.0620152091119e-05 | 0.00399826821885042 | 0.00327929137082121 | ASAP1/GSK3B/HTT/PIP4K2A/SEPTIN7 | 5 |
| MeSH_gene2pubmed | B_13_10 | D020394 | Vault Ribonucleoprotein Particles | 4/74 | 58/26076 | 2.25723005878898e-05 | 0.0034484319216317 | 0.00272811632942629 | LRPPRC/PTEN/PTPN11/RO60 | 4 |
| MeSH_gene2pubmed | B_13_10 | D051419 | D051419 | 7/74 | 302/26076 | 2.41643723831152e-05 | 0.00353115024259349 | 0.00279355627641872 | ASAP1/EPS15/GSK3B/PTEN/PTPN11/PTPRA/SH3KBP1 | 7 |
| GO | B_13_10 | GO:0071375 | cellular response to peptide hormone stimulus | 8/71 | 321/18986 | 2.58068635461904e-05 | 0.00399826821885042 | 0.00327929137082121 | GSK3B/PIP4K2A/PTPN11/PTPN2/PTPRA/ROCK2/SMARCC1/SOS2 | 8 |
| MeSH_gene2pubmed | B_13_10 | D051788 | Myeloid-Lymphoid Leukemia Protein | 6/74 | 205/26076 | 2.60535617201146e-05 | 0.00364858420588772 | 0.0028864603905706 | EPS15/FNBP1/GSK3B/PTPN11/SMARCC1/SOS2 | 6 |
| GO | B_13_10 | GO:1902115 | regulation of organelle assembly | 7/71 | 234/18986 | 2.68658621494364e-05 | 0.00399826821885042 | 0.00327929137082121 | ASAP1/GSK3B/HTT/MAP4/PIP4K2A/SEPTIN7/TPR | 7 |
| GO | B_13_10 | GO:0018105 | peptidyl-serine phosphorylation | 6/71 | 159/18986 | 2.86812306948897e-05 | 0.00399826821885042 | 0.00327929137082121 | ATR/GSK3B/MARK2/PTEN/RPS6KA3/WNK1 | 6 |