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Selected Module: B_13_10
Module Info
| Module_Name | B_13_10 |
| Cell_Type | B |
| Name | B_13_10: Intercellular Junctions |
| Meta_Module | B_6 |
| Gene_Number | 74 |
Genes:
AGFG1, ANGEL2, ASAP1, ATR, BLTP3B, CDK11B, CERT1, CLSTN1, CMIP, CUL2, DOCK2, EEA1, EFR3A, EPS15, ERCC6L2, EXOC1, FNBP1, FXR1, G2E3, GABPB2, GALNT10, GGA2, GNB1, GSK3B, HTT, IPO7, KDM6A, KIAA0586, LRPPRC, MAP4, MARK2, MED17, MLH3, MPRIP, MYO9B, NCBP3, PDS5A, PHF6, PI4KA, PIP4K2A, PPIP5K2, PPP1R12A, PTEN, PTPN11, PTPN2, PTPRA, RBM19, RO60, ROCK2, RPS6KA3, SEPTIN7, SH3KBP1, SLC25A32, SMARCC1, SNRK, SOS2, STX17, TBL1XR1, TENT4B, TGOLN2, TMOD3, TNK2, TPR, UBR4, UBXN2A, VEZT, WDR20, WNK1, XIST, ZBTB40, ZC3H8, ZDHHC17, ZMYM4, ZMYND11
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| ETF | 0.00814695694547425 | CLSTN1/CUL2/GNB1/RO60/UBR4 |
| NFMUE1 | 0.0104026073134015 | CERT1/CLSTN1/GABPB2/KDM6A/RBM19/SEPTIN7 |
| RRAGTTGT | 0.0104026073134015 | CERT1/EPS15/IPO7/KDM6A/RPS6KA3/TMOD3 |
| RRCCGTTA | 0.0110610281088081 | FXR1/KIAA0586/UBR4/ZMYM4 |
| E2F | 0.0117162801242734 | CLSTN1/GNB1/PIP4K2A/TPR/ZMYM4 |
| E4BP4 | 0.0263722148756448 | CLSTN1/FNBP1/KDM6A/MAP4/RPS6KA3 |
| NPM1 | 0.0288762278591829 | ERCC6L2/NCBP3/PPP1R12A/RO60/SEPTIN7/TGOLN2 |
| ZIC2 | 0.0341299648703405 | FNBP1/KDM6A/MAP4/PHF6/ZMYND11 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_13_10 | D055765 | Shc Signaling Adaptor Proteins | 8/74 | 279/26076 | 1.27113853088228e-06 | 0.00039891297504628 | 0.00031558720774422 | ATR/HTT/PI4KA/PTEN/PTPN11/PTPN2/PTPRA/SOS2 | 8 |
| MeSH_gene2pubmed | B_13_10 | D020931 | ran GTP-Binding Protein | 8/74 | 280/26076 | 1.30557653243353e-06 | 0.00039891297504628 | 0.00031558720774422 | AGFG1/ATR/CDK11B/CUL2/GSK3B/IPO7/PTEN/TPR | 8 |
| MeSH_gene2pubmed | B_13_10 | D014168 | Transferrin | 10/74 | 500/26076 | 1.47150985147283e-06 | 0.00041214538423334 | 0.00032605560393161 | ASAP1/EEA1/EPS15/FNBP1/GGA2/HTT/MAP4/PTEN/SH3KBP1/TGOLN2 | 10 |
| WikiPathways | B_13_10 | WP437 | EGF EGFR signaling | 8/47 | 159/8836 | 1.59716431136315e-06 | 0.0003162385336499 | 0.00024714016186356 | ASAP1/EPS15/PTEN/PTPN11/RPS6KA3/SH3KBP1/SOS2/TNK2 | 8 |
| MeSH_gene2pubmed | B_13_10 | D019269 | Phosphatidylinositol 4,5-Diphosphate | 8/74 | 298/26076 | 2.07636271891918e-06 | 0.00053681962294518 | 0.00042468762979674 | ASAP1/FNBP1/HTT/PI4KA/PIP4K2A/PTEN/SMARCC1/TGOLN2 | 8 |
| GO | B_13_10 | GO:0051236 | establishment of RNA localization | 7/71 | 167/18986 | 2.97604459703533e-06 | 0.00261445517849554 | 0.00214431844912704 | AGFG1/ATR/FXR1/LRPPRC/NCBP3/TPR/WNK1 | 7 |
| GO | B_13_10 | GO:0044024 | histone H2AS1 kinase activity | 8/73 | 246/18737 | 5.07480683189638e-06 | 0.00050986053241391 | 0.00041027373836347 | ATR/GSK3B/MARK2/ROCK2/RPS6KA3/SNRK/TNK2/WNK1 | 8 |
| GO | B_13_10 | GO:0140995 | histone H2A kinase activity | 8/73 | 246/18737 | 5.07480683189638e-06 | 0.00050986053241391 | 0.00041027373836347 | ATR/GSK3B/MARK2/ROCK2/RPS6KA3/SNRK/TNK2/WNK1 | 8 |
| GO | B_13_10 | GO:0045724 | positive regulation of cilium assembly | 4/71 | 31/18986 | 5.23383564999993e-06 | 0.00306528307901662 | 0.00251407754556137 | ASAP1/GSK3B/HTT/SEPTIN7 | 4 |
| GO | B_13_10 | GO:0035173 | histone kinase activity | 8/73 | 256/18737 | 6.79814043218555e-06 | 0.00050986053241391 | 0.00041027373836347 | ATR/GSK3B/MARK2/ROCK2/RPS6KA3/SNRK/TNK2/WNK1 | 8 |