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Selected Module: B_13_10
Module Info
| Module_Name | B_13_10 |
| Cell_Type | B |
| Name | B_13_10: Intercellular Junctions |
| Meta_Module | B_6 |
| Gene_Number | 74 |
Genes:
AGFG1, ANGEL2, ASAP1, ATR, BLTP3B, CDK11B, CERT1, CLSTN1, CMIP, CUL2, DOCK2, EEA1, EFR3A, EPS15, ERCC6L2, EXOC1, FNBP1, FXR1, G2E3, GABPB2, GALNT10, GGA2, GNB1, GSK3B, HTT, IPO7, KDM6A, KIAA0586, LRPPRC, MAP4, MARK2, MED17, MLH3, MPRIP, MYO9B, NCBP3, PDS5A, PHF6, PI4KA, PIP4K2A, PPIP5K2, PPP1R12A, PTEN, PTPN11, PTPN2, PTPRA, RBM19, RO60, ROCK2, RPS6KA3, SEPTIN7, SH3KBP1, SLC25A32, SMARCC1, SNRK, SOS2, STX17, TBL1XR1, TENT4B, TGOLN2, TMOD3, TNK2, TPR, UBR4, UBXN2A, VEZT, WDR20, WNK1, XIST, ZBTB40, ZC3H8, ZDHHC17, ZMYM4, ZMYND11
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| ETF | 0.00814695694547425 | CLSTN1/CUL2/GNB1/RO60/UBR4 |
| NFMUE1 | 0.0104026073134015 | CERT1/CLSTN1/GABPB2/KDM6A/RBM19/SEPTIN7 |
| RRAGTTGT | 0.0104026073134015 | CERT1/EPS15/IPO7/KDM6A/RPS6KA3/TMOD3 |
| RRCCGTTA | 0.0110610281088081 | FXR1/KIAA0586/UBR4/ZMYM4 |
| E2F | 0.0117162801242734 | CLSTN1/GNB1/PIP4K2A/TPR/ZMYM4 |
| E4BP4 | 0.0263722148756448 | CLSTN1/FNBP1/KDM6A/MAP4/RPS6KA3 |
| NPM1 | 0.0288762278591829 | ERCC6L2/NCBP3/PPP1R12A/RO60/SEPTIN7/TGOLN2 |
| ZIC2 | 0.0341299648703405 | FNBP1/KDM6A/MAP4/PHF6/ZMYND11 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_13_10 | GO:0006999 | nuclear pore organization | 2/71 | 15/18986 | 0.00140289910161483 | 0.0481970351757058 | 0.0395301447776061 | FXR1/TPR | 2 |
| GO | B_13_10 | GO:0045059 | positive thymic T cell selection | 2/71 | 15/18986 | 0.00140289910161483 | 0.0481970351757058 | 0.0395301447776061 | DOCK2/PTPN2 | 2 |
| MeSH_gene2pubmed | B_13_10 | D018106 | CD28 Antigens | 6/74 | 431/26076 | 0.00141452568280751 | 0.0431321010341466 | 0.0341225785597189 | DOCK2/PTEN/PTPN11/RO60/RPS6KA3/SOS2 | 6 |
| MeSH_gene2pubmed | B_13_10 | D015388 | Organelles | 6/74 | 432/26076 | 0.00143126742277403 | 0.0431321010341466 | 0.0341225785597189 | CERT1/EEA1/EPS15/HTT/MAP4/TGOLN2 | 6 |
| MeSH_gene2pubmed | B_13_10 | D051178 | alpha Catenin | 4/74 | 171/26076 | 0.00143730893062315 | 0.0431321010341466 | 0.0341225785597189 | GSK3B/PTEN/PTPN11/VEZT | 4 |
| GO | B_13_10 | GO:0022411 | cellular component disassembly | 7/71 | 450/18986 | 0.00144384527133967 | 0.0481970351757058 | 0.0395301447776061 | ATR/GSK3B/MAP4/SMARCC1/STX17/TMOD3/WNK1 | 7 |
| GO | B_13_10 | GO:0051020 | GTPase binding | 6/73 | 316/18737 | 0.00144747240150614 | 0.02326294930992 | 0.0187191919593275 | DOCK2/GGA2/GNB1/IPO7/MYO9B/ROCK2 | 6 |
| GO | B_13_10 | GO:0016311 | dephosphorylation | 5/71 | 222/18986 | 0.0014538661720617 | 0.0481970351757058 | 0.0395301447776061 | PPP1R12A/PTEN/PTPN11/PTPN2/PTPRA | 5 |
| MeSH_gene2pubmed | B_13_10 | D018871 | Endoplasmic Reticulum, Smooth | 2/74 | 20/26076 | 0.0014603718513453 | 0.043436369843996 | 0.0343632910712457 | STX17/TGOLN2 | 2 |
| MeSH_gene2pubmed | B_13_10 | D020797 | Receptor, Platelet-Derived Growth Factor beta | 4/74 | 174/26076 | 0.00153199351878137 | 0.0451669317247735 | 0.0357323696070335 | FNBP1/PTEN/PTPN11/PTPN2 | 4 |