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Selected Module: B_13_10
Module Info
| Module_Name | B_13_10 |
| Cell_Type | B |
| Name | B_13_10: Intercellular Junctions |
| Meta_Module | B_6 |
| Gene_Number | 74 |
Genes:
AGFG1, ANGEL2, ASAP1, ATR, BLTP3B, CDK11B, CERT1, CLSTN1, CMIP, CUL2, DOCK2, EEA1, EFR3A, EPS15, ERCC6L2, EXOC1, FNBP1, FXR1, G2E3, GABPB2, GALNT10, GGA2, GNB1, GSK3B, HTT, IPO7, KDM6A, KIAA0586, LRPPRC, MAP4, MARK2, MED17, MLH3, MPRIP, MYO9B, NCBP3, PDS5A, PHF6, PI4KA, PIP4K2A, PPIP5K2, PPP1R12A, PTEN, PTPN11, PTPN2, PTPRA, RBM19, RO60, ROCK2, RPS6KA3, SEPTIN7, SH3KBP1, SLC25A32, SMARCC1, SNRK, SOS2, STX17, TBL1XR1, TENT4B, TGOLN2, TMOD3, TNK2, TPR, UBR4, UBXN2A, VEZT, WDR20, WNK1, XIST, ZBTB40, ZC3H8, ZDHHC17, ZMYM4, ZMYND11
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| ETF | 0.00814695694547425 | CLSTN1/CUL2/GNB1/RO60/UBR4 |
| NFMUE1 | 0.0104026073134015 | CERT1/CLSTN1/GABPB2/KDM6A/RBM19/SEPTIN7 |
| RRAGTTGT | 0.0104026073134015 | CERT1/EPS15/IPO7/KDM6A/RPS6KA3/TMOD3 |
| RRCCGTTA | 0.0110610281088081 | FXR1/KIAA0586/UBR4/ZMYM4 |
| E2F | 0.0117162801242734 | CLSTN1/GNB1/PIP4K2A/TPR/ZMYM4 |
| E4BP4 | 0.0263722148756448 | CLSTN1/FNBP1/KDM6A/MAP4/RPS6KA3 |
| NPM1 | 0.0288762278591829 | ERCC6L2/NCBP3/PPP1R12A/RO60/SEPTIN7/TGOLN2 |
| ZIC2 | 0.0341299648703405 | FNBP1/KDM6A/MAP4/PHF6/ZMYND11 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_13_10 | D002070 | Butadienes | 6/74 | 384/26076 | 0.00078201006484318 | 0.0316666967221438 | 0.0250520916143802 | GSK3B/PTEN/PTPN11/PTPRA/RPS6KA3/WNK1 | 6 |
| GO | B_13_10 | GO:0006892 | post-Golgi vesicle-mediated transport | 4/71 | 111/18986 | 0.00079544441824004 | 0.03583579084225 | 0.0293917249276819 | ASAP1/EPS15/EXOC1/GGA2 | 4 |
| MeSH_gene2pubmed | B_13_10 | D004428 | Ear Neoplasms | 2/74 | 15/26076 | 0.00081449450513328 | 0.0322060709617995 | 0.0254788002472652 | CUL2/PTEN | 2 |
| MeSH_gene2pubmed | B_13_10 | D007911 | Lentigo | 2/74 | 15/26076 | 0.00081449450513328 | 0.0322060709617995 | 0.0254788002472652 | PTEN/PTPN11 | 2 |
| GO | B_13_10 | GO:0120034 | positive regulation of plasma membrane bounded cell projection assembly | 4/71 | 113/18986 | 0.00085039534845435 | 0.0373536156808577 | 0.0306366113693163 | ASAP1/GSK3B/HTT/SEPTIN7 | 4 |
| MeSH_gene2pubmed | B_13_10 | D051718 | MutS Homolog 2 Protein | 4/74 | 149/26076 | 0.00086372016209445 | 0.033507332652962 | 0.0265082517049694 | ATR/HTT/MLH3/PTEN | 4 |
| MeSH_gene2pubmed | B_13_10 | D020687 | cdc25 Phosphatases | 5/74 | 260/26076 | 0.00087219000067211 | 0.033507332652962 | 0.0265082517049694 | ATR/GSK3B/PTEN/PTPN11/PTPRA | 5 |
| MeSH_gene2pubmed | B_13_10 | D011990 | Receptors, Transferrin | 6/74 | 393/26076 | 0.00088162810508893 | 0.033507332652962 | 0.0265082517049694 | ASAP1/EEA1/EPS15/HTT/SH3KBP1/TGOLN2 | 6 |
| MeSH_gene2pubmed | B_13_10 | D050717 | Retinoblastoma-Like Protein p130 | 5/74 | 261/26076 | 0.00088728134665683 | 0.033507332652962 | 0.0265082517049694 | PTEN/PTPN11/PTPRA/SH3KBP1/TNK2 | 5 |
| GO | B_13_10 | GO:0033629 | negative regulation of cell adhesion mediated by integrin | 2/71 | 12/18986 | 0.00088824481604248 | 0.0380645400435766 | 0.0312196958449848 | PTPN11/WNK1 | 2 |