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Selected Module: B_13_10


Module Info

Module_Name B_13_10
Cell_Type B
Name B_13_10: Intercellular Junctions
Meta_Module B_6
Gene_Number 74

Genes:

AGFG1, ANGEL2, ASAP1, ATR, BLTP3B, CDK11B, CERT1, CLSTN1, CMIP, CUL2, DOCK2, EEA1, EFR3A, EPS15, ERCC6L2, EXOC1, FNBP1, FXR1, G2E3, GABPB2, GALNT10, GGA2, GNB1, GSK3B, HTT, IPO7, KDM6A, KIAA0586, LRPPRC, MAP4, MARK2, MED17, MLH3, MPRIP, MYO9B, NCBP3, PDS5A, PHF6, PI4KA, PIP4K2A, PPIP5K2, PPP1R12A, PTEN, PTPN11, PTPN2, PTPRA, RBM19, RO60, ROCK2, RPS6KA3, SEPTIN7, SH3KBP1, SLC25A32, SMARCC1, SNRK, SOS2, STX17, TBL1XR1, TENT4B, TGOLN2, TMOD3, TNK2, TPR, UBR4, UBXN2A, VEZT, WDR20, WNK1, XIST, ZBTB40, ZC3H8, ZDHHC17, ZMYM4, ZMYND11


UMAP Visualizations


UMAP for B_13_10

UMAP for B_13_10


Word Cloud

Enriched TF

Wordcloud for B_13_10
TF p.adjust Genes
ETF 0.00814695694547425 CLSTN1/CUL2/GNB1/RO60/UBR4
NFMUE1 0.0104026073134015 CERT1/CLSTN1/GABPB2/KDM6A/RBM19/SEPTIN7
RRAGTTGT 0.0104026073134015 CERT1/EPS15/IPO7/KDM6A/RPS6KA3/TMOD3
RRCCGTTA 0.0110610281088081 FXR1/KIAA0586/UBR4/ZMYM4
E2F 0.0117162801242734 CLSTN1/GNB1/PIP4K2A/TPR/ZMYM4
E4BP4 0.0263722148756448 CLSTN1/FNBP1/KDM6A/MAP4/RPS6KA3
NPM1 0.0288762278591829 ERCC6L2/NCBP3/PPP1R12A/RO60/SEPTIN7/TGOLN2
ZIC2 0.0341299648703405 FNBP1/KDM6A/MAP4/PHF6/ZMYND11


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_13_10 GO:0048156 tau protein binding 3/73 43/18737 0.00062606892550205 0.0133335556596194 0.0107292237354599 GSK3B/MARK2/ROCK2 3
MeSH_gene2pubmed B_13_10 D029543 Nucleocytoplasmic Transport Proteins 5/74 243/26076 0.00064380433763497 0.0273902073264704 0.0216688841687669 AGFG1/CDK11B/SOS2/TPR/XIST 5
GO B_13_10 GO:0004721 phosphoprotein phosphatase activity 5/73 178/18737 0.00065186272113695 0.0133335556596194 0.0107292237354599 HTT/PTEN/PTPN11/PTPN2/PTPRA 5
GO B_13_10 GO:0098687 chromosomal region 7/73 404/19960 0.00068257853534191 0.029896939847976 0.0244291265280265 ATR/PDS5A/PHF6/PPP1R12A/SEPTIN7/SMARCC1/TPR 7
MeSH_gene2pubmed B_13_10 D019706 Excitatory Postsynaptic Potentials 4/74 141/26076 0.00070291334964211 0.0295311471018394 0.0233626200157367 EEA1/FXR1/PTPN11/SEPTIN7 4
GO B_13_10 GO:0060271 cilium assembly 7/71 398/18986 0.00070805137662834 0.0343076284296914 0.0281383598359929 ASAP1/GSK3B/HTT/KIAA0586/MAP4/RO60/SEPTIN7 7
MeSH_gene2pubmed B_13_10 D042846 CDC2-CDC28 Kinases 6/74 380/26076 0.00074064108297065 0.0307320330847452 0.0243126624507325 ATR/CDK11B/CUL2/GSK3B/IPO7/PTEN 6
GO B_13_10 GO:0033085 negative regulation of T cell differentiation in thymus 2/71 11/18986 0.00074199765528074 0.0343076284296914 0.0281383598359929 PTPN2/ZC3H8 2
GO B_13_10 GO:1902855 regulation of non-motile cilium assembly 2/71 11/18986 0.00074199765528074 0.0343076284296914 0.0281383598359929 MAP4/SEPTIN7 2
MeSH_gene2pubmed B_13_10 D010761 Phosphorus Radioisotopes 5/74 252/26076 0.00075825317051071 0.0310791330010549 0.0245872594186144 ASAP1/ATR/GSK3B/MAP4/PTPN11 5