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Selected Module: B_13_10


Module Info

Module_Name B_13_10
Cell_Type B
Name B_13_10: Intercellular Junctions
Meta_Module B_6
Gene_Number 74

Genes:

AGFG1, ANGEL2, ASAP1, ATR, BLTP3B, CDK11B, CERT1, CLSTN1, CMIP, CUL2, DOCK2, EEA1, EFR3A, EPS15, ERCC6L2, EXOC1, FNBP1, FXR1, G2E3, GABPB2, GALNT10, GGA2, GNB1, GSK3B, HTT, IPO7, KDM6A, KIAA0586, LRPPRC, MAP4, MARK2, MED17, MLH3, MPRIP, MYO9B, NCBP3, PDS5A, PHF6, PI4KA, PIP4K2A, PPIP5K2, PPP1R12A, PTEN, PTPN11, PTPN2, PTPRA, RBM19, RO60, ROCK2, RPS6KA3, SEPTIN7, SH3KBP1, SLC25A32, SMARCC1, SNRK, SOS2, STX17, TBL1XR1, TENT4B, TGOLN2, TMOD3, TNK2, TPR, UBR4, UBXN2A, VEZT, WDR20, WNK1, XIST, ZBTB40, ZC3H8, ZDHHC17, ZMYM4, ZMYND11


UMAP Visualizations


UMAP for B_13_10

UMAP for B_13_10


Word Cloud

Enriched TF

Wordcloud for B_13_10
TF p.adjust Genes
ETF 0.00814695694547425 CLSTN1/CUL2/GNB1/RO60/UBR4
NFMUE1 0.0104026073134015 CERT1/CLSTN1/GABPB2/KDM6A/RBM19/SEPTIN7
RRAGTTGT 0.0104026073134015 CERT1/EPS15/IPO7/KDM6A/RPS6KA3/TMOD3
RRCCGTTA 0.0110610281088081 FXR1/KIAA0586/UBR4/ZMYM4
E2F 0.0117162801242734 CLSTN1/GNB1/PIP4K2A/TPR/ZMYM4
E4BP4 0.0263722148756448 CLSTN1/FNBP1/KDM6A/MAP4/RPS6KA3
NPM1 0.0288762278591829 ERCC6L2/NCBP3/PPP1R12A/RO60/SEPTIN7/TGOLN2
ZIC2 0.0341299648703405 FNBP1/KDM6A/MAP4/PHF6/ZMYND11


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_13_10 GO:0009895 negative regulation of catabolic process 7/71 367/18986 0.00043779608611072 0.0228536342674921 0.0187440465579467 ANGEL2/FXR1/LRPPRC/SMARCC1/TENT4B/UBXN2A/WNK1 7
GO B_13_10 GO:0006405 RNA export from nucleus 4/71 95/18986 0.00044224448781715 0.0228536342674921 0.0187440465579467 AGFG1/NCBP3/TPR/WNK1 4
MeSH_gene2pubmed B_13_10 D018386 Kinetochores 5/74 224/26076 0.00044514552854473 0.0230174480221362 0.0182095158721295 GSK3B/PPP1R12A/RPS6KA3/SEPTIN7/SMARCC1 5
MeSH_gene2pubmed B_13_10 D051417 Focal Adhesion Kinase 1 7/74 486/26076 0.00045880424860477 0.023171900828955 0.0183317062572043 ASAP1/GSK3B/MPRIP/PTEN/PTPN11/PTPRA/SH3KBP1 7
MeSH_gene2pubmed B_13_10 D003561 Cytarabine 5/74 227/26076 0.00047292909462639 0.023171900828955 0.0183317062572043 ATR/MAP4/PTEN/PTPN11/PTPRA 5
MeSH_gene2pubmed B_13_10 D051572 Proto-Oncogene Proteins c-hck 4/74 127/26076 0.00047439093903678 0.023171900828955 0.0183317062572043 ASAP1/DOCK2/SH3KBP1/TNK2 4
MeSH_gene2pubmed B_13_10 D019108 Tight Junctions 7/74 491/26076 0.00048759951164536 0.023171900828955 0.0183317062572043 MARK2/PPP1R12A/PTEN/PTPN11/ROCK2/SH3KBP1/TBL1XR1 7
MeSH_gene2pubmed B_13_10 D010712 Phosphatidic Acids 4/74 128/26076 0.00048864996437759 0.023171900828955 0.0183317062572043 ASAP1/PIP4K2A/PPP1R12A/PTPN11 4
MeSH_gene2pubmed B_13_10 D038762 Ribosomal Protein S6 Kinases, 70-kDa 5/74 229/26076 0.00049216465537543 0.023171900828955 0.0183317062572043 ATR/GSK3B/PTEN/PTPN11/WNK1 5
MeSH_gene2pubmed B_13_10 D050826 Suppressor of Cytokine Signaling Proteins 6/74 352/26076 0.00049639299603831 0.023171900828955 0.0183317062572043 ATR/CUL2/PTPN11/PTPN2/SEPTIN7/SOS2 6