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Selected Module: B_13_10
Module Info
| Module_Name | B_13_10 |
| Cell_Type | B |
| Name | B_13_10: Intercellular Junctions |
| Meta_Module | B_6 |
| Gene_Number | 74 |
Genes:
AGFG1, ANGEL2, ASAP1, ATR, BLTP3B, CDK11B, CERT1, CLSTN1, CMIP, CUL2, DOCK2, EEA1, EFR3A, EPS15, ERCC6L2, EXOC1, FNBP1, FXR1, G2E3, GABPB2, GALNT10, GGA2, GNB1, GSK3B, HTT, IPO7, KDM6A, KIAA0586, LRPPRC, MAP4, MARK2, MED17, MLH3, MPRIP, MYO9B, NCBP3, PDS5A, PHF6, PI4KA, PIP4K2A, PPIP5K2, PPP1R12A, PTEN, PTPN11, PTPN2, PTPRA, RBM19, RO60, ROCK2, RPS6KA3, SEPTIN7, SH3KBP1, SLC25A32, SMARCC1, SNRK, SOS2, STX17, TBL1XR1, TENT4B, TGOLN2, TMOD3, TNK2, TPR, UBR4, UBXN2A, VEZT, WDR20, WNK1, XIST, ZBTB40, ZC3H8, ZDHHC17, ZMYM4, ZMYND11
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| ETF | 0.00814695694547425 | CLSTN1/CUL2/GNB1/RO60/UBR4 |
| NFMUE1 | 0.0104026073134015 | CERT1/CLSTN1/GABPB2/KDM6A/RBM19/SEPTIN7 |
| RRAGTTGT | 0.0104026073134015 | CERT1/EPS15/IPO7/KDM6A/RPS6KA3/TMOD3 |
| RRCCGTTA | 0.0110610281088081 | FXR1/KIAA0586/UBR4/ZMYM4 |
| E2F | 0.0117162801242734 | CLSTN1/GNB1/PIP4K2A/TPR/ZMYM4 |
| E4BP4 | 0.0263722148756448 | CLSTN1/FNBP1/KDM6A/MAP4/RPS6KA3 |
| NPM1 | 0.0288762278591829 | ERCC6L2/NCBP3/PPP1R12A/RO60/SEPTIN7/TGOLN2 |
| ZIC2 | 0.0341299648703405 | FNBP1/KDM6A/MAP4/PHF6/ZMYND11 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_13_10 | D051357 | Cyclin-Dependent Kinase 2 | 7/74 | 458/26076 | 0.00032164071108382 | 0.0179181306088332 | 0.0141753544270698 | ATR/CDK11B/CUL2/GSK3B/IPO7/PTEN/PTPN11 | 7 |
| MeSH_gene2pubmed | B_13_10 | D019804 | Mesalamine | 3/74 | 47/26076 | 0.00032520260849117 | 0.0179181306088332 | 0.0141753544270698 | ATR/PTEN/PTPN11 | 3 |
| GO | B_13_10 | GO:0046825 | regulation of protein export from nucleus | 3/71 | 36/18986 | 0.00032749306313569 | 0.0191801770643136 | 0.0157311580151846 | GSK3B/PTPN11/TPR | 3 |
| MeSH_gene2pubmed | B_13_10 | D000590 | Amino Acid Chloromethyl Ketones | 6/74 | 328/26076 | 0.00034169263831622 | 0.0185230476996907 | 0.0146539151848349 | AGFG1/ATR/HTT/PTEN/RO60/TGOLN2 | 6 |
| GO | B_13_10 | GO:0033077 | T cell differentiation in thymus | 4/71 | 89/18986 | 0.00034494386782134 | 0.0195505282503902 | 0.0160349118861601 | DOCK2/PTPN2/SOS2/ZC3H8 | 4 |
| MeSH_gene2pubmed | B_13_10 | D020725 | ral GTP-Binding Proteins | 4/74 | 117/26076 | 0.00034765482050977 | 0.0185471087576725 | 0.0146729503192598 | AGFG1/EPS15/EXOC1/PTEN | 4 |
| MeSH_gene2pubmed | B_13_10 | D020663 | ras Guanine Nucleotide Exchange Factors | 4/74 | 119/26076 | 0.00037078298319805 | 0.0194719001020105 | 0.0154045693348404 | GNB1/PTPN11/SOS2/TNK2 | 4 |
| GO | B_13_10 | GO:1902369 | negative regulation of RNA catabolic process | 4/71 | 92/18986 | 0.00039143567021229 | 0.0214922647675939 | 0.0176274813329156 | ANGEL2/FXR1/LRPPRC/TENT4B | 4 |
| GO | B_13_10 | GO:0000775 | chromosome, centromeric region | 6/73 | 262/19960 | 0.00039404706109588 | 0.029896939847976 | 0.0244291265280265 | PDS5A/PHF6/PPP1R12A/SEPTIN7/SMARCC1/TPR | 6 |
| GO | B_13_10 | GO:0000776 | kinetochore | 5/73 | 173/19960 | 0.00043076734328304 | 0.029896939847976 | 0.0244291265280265 | PHF6/PPP1R12A/SEPTIN7/SMARCC1/TPR | 5 |