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Selected Module: B_13_10


Module Info

Module_Name B_13_10
Cell_Type B
Name B_13_10: Intercellular Junctions
Meta_Module B_6
Gene_Number 74

Genes:

AGFG1, ANGEL2, ASAP1, ATR, BLTP3B, CDK11B, CERT1, CLSTN1, CMIP, CUL2, DOCK2, EEA1, EFR3A, EPS15, ERCC6L2, EXOC1, FNBP1, FXR1, G2E3, GABPB2, GALNT10, GGA2, GNB1, GSK3B, HTT, IPO7, KDM6A, KIAA0586, LRPPRC, MAP4, MARK2, MED17, MLH3, MPRIP, MYO9B, NCBP3, PDS5A, PHF6, PI4KA, PIP4K2A, PPIP5K2, PPP1R12A, PTEN, PTPN11, PTPN2, PTPRA, RBM19, RO60, ROCK2, RPS6KA3, SEPTIN7, SH3KBP1, SLC25A32, SMARCC1, SNRK, SOS2, STX17, TBL1XR1, TENT4B, TGOLN2, TMOD3, TNK2, TPR, UBR4, UBXN2A, VEZT, WDR20, WNK1, XIST, ZBTB40, ZC3H8, ZDHHC17, ZMYM4, ZMYND11


UMAP Visualizations


UMAP for B_13_10

UMAP for B_13_10


Word Cloud

Enriched TF

Wordcloud for B_13_10
TF p.adjust Genes
ETF 0.00814695694547425 CLSTN1/CUL2/GNB1/RO60/UBR4
NFMUE1 0.0104026073134015 CERT1/CLSTN1/GABPB2/KDM6A/RBM19/SEPTIN7
RRAGTTGT 0.0104026073134015 CERT1/EPS15/IPO7/KDM6A/RPS6KA3/TMOD3
RRCCGTTA 0.0110610281088081 FXR1/KIAA0586/UBR4/ZMYM4
E2F 0.0117162801242734 CLSTN1/GNB1/PIP4K2A/TPR/ZMYM4
E4BP4 0.0263722148756448 CLSTN1/FNBP1/KDM6A/MAP4/RPS6KA3
NPM1 0.0288762278591829 ERCC6L2/NCBP3/PPP1R12A/RO60/SEPTIN7/TGOLN2
ZIC2 0.0341299648703405 FNBP1/KDM6A/MAP4/PHF6/ZMYND11


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_13_10 GO:0043434 response to peptide hormone 8/71 446/18986 0.00025372752263493 0.016511083602577 0.0135420264517436 GSK3B/PIP4K2A/PTPN11/PTPN2/PTPRA/ROCK2/SMARCC1/SOS2 8
hallmark B_13_10 HALLMARK_PI3K_AKT_MTOR_SIGNALING HALLMARK_PI3K_AKT_MTOR_SIGNALING 4/14 105/4384 0.0002585613953214 0.00465410511578528 0.00408254834718007 GSK3B/PTEN/PTPN11/RPS6KA3 4
GO B_13_10 GO:0006997 nucleus organization 5/71 153/18986 0.00027008804736442 0.0169480249721174 0.0139003961218756 AGFG1/ATR/FXR1/TPR/UBXN2A 5
MeSH_gene2pubmed B_13_10 D016044 Fusion Proteins, bcr-abl 6/74 314/26076 0.00027077527665348 0.0168492576706201 0.0133297498789478 ATR/PTEN/PTPN11/PTPN2/SOS2/TNK2 6
MeSH_gene2pubmed B_13_10 D019680 Trinucleotide Repeat Expansion 5/74 202/26076 0.00027721885010471 0.0168492576706201 0.0133297498789478 ATR/FXR1/HTT/PTEN/ZDHHC17 5
MeSH_gene2pubmed B_13_10 D008546 Melanoma, Experimental 6/74 317/26076 0.00028489496839918 0.0168492576706201 0.0133297498789478 GSK3B/PPP1R12A/PTEN/RO60/ROCK2/TGOLN2 6
MeSH_gene2pubmed B_13_10 D054594 Protein Tyrosine Phosphatase, Non-Receptor Type 12 3/74 45/26076 0.00028575057638362 0.0168492576706201 0.0133297498789478 PTPN11/PTPN2/SH3KBP1 3
MeSH_gene2pubmed B_13_10 D016391 Genes, src 5/74 205/26076 0.00029668614290188 0.0171924504533318 0.0136012558433788 EPS15/PTEN/PTPN11/PTPRA/SOS2 5
GO B_13_10 GO:0098876 vesicle-mediated transport to the plasma membrane 5/71 157/18986 0.0003042813024165 0.0184352499429583 0.0151201852271575 ASAP1/CLSTN1/EPS15/EXOC1/GGA2 5
MeSH_gene2pubmed B_13_10 D011985 Receptors, Serotonin 5/74 207/26076 0.0003102292318755 0.0176725499717553 0.0139810711814008 GSK3B/HTT/PTEN/PTPRA/RO60 5