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Selected Module: B_12_9
Module Info
| Module_Name | B_12_9 |
| Cell_Type | B |
| Name | B_12_9: Endocytosis |
| Meta_Module | B_17 |
| Gene_Number | 56 |
Genes:
ACAP2, ADD3, ANKZF1, AP1M1, AP2B1, ARHGAP15, ARNT, ASXL2, CALCOCO2, CEP170, CEP57, CRYBG1, CUL1, CYFIP2, DENND4C, DIP2B, DYM, EPS15L1, ERCC5, EXOSC10, FAM78A, FGD3, FIP1L1, FLI1, GIT2, HMG20A, JAZF1, MCM3AP, NBPF14, NCOR1, PIK3CD, PPIG, PPP1R16B, PRKACB, RAB14, RABEP2, RIGI, RIPOR2, RMC1, RNF111, RNF20, RNFT1, RPRD2, SLC25A24, SLC44A2, SNX1, SPIDR, SPTLC2, TCF12, TNFAIP8, TRAK2, TTN, UHMK1, VPS39, WASHC2A, ZNF512
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| CETS1P54 | 0.0496577873122401 | AP1M1/HMG20A/PPIG/PRKACB/UHMK1 |
| TAAYNRNNTCC | 0.0496577873122401 | AP2B1/DIP2B/NCOR1/PPIG |
| PAX5 | 0.0496577873122401 | AP2B1/FLI1 |
| NKX3A | 0.0496577873122401 | DIP2B/RNF111/TCF12/ZNF512 |
| TEL2 | 0.0496577873122401 | ARHGAP15/PRKACB/SNX1/TCF12 |
| CMYB | 0.0496577873122401 | ADD3/AP2B1/ASXL2/PPIG |
| COMP1 | 0.0496577873122401 | DENND4C/FLI1/TCF12 |
| ELK1 | 0.0496577873122401 | AP1M1/HMG20A/PPIG/PRKACB |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| KEGG | B_12_9 | hsa04144 | Endocytosis | 6/27 | 252/8541 | 0.0001092092147237 | 0.018783984932478 | 0.0168986890151424 | ACAP2/AP2B1/EPS15L1/GIT2/SNX1/WASHC2A | 6 |
| GO | B_12_9 | GO:0030117 | membrane coat | 4/55 | 97/19960 | 0.00014781511664303 | 0.010189410955248 | 0.00763174504745297 | AP1M1/AP2B1/EPS15L1/VPS39 | 4 |
| GO | B_12_9 | GO:0048475 | coated membrane | 4/55 | 97/19960 | 0.00014781511664303 | 0.010189410955248 | 0.00763174504745297 | AP1M1/AP2B1/EPS15L1/VPS39 | 4 |
| GO | B_12_9 | GO:0030119 | AP-type membrane coat adaptor complex | 3/55 | 41/19960 | 0.00019595021067784 | 0.010189410955248 | 0.00763174504745297 | AP1M1/AP2B1/VPS39 | 3 |
| GO | B_12_9 | GO:0030118 | clathrin coat | 3/55 | 51/19960 | 0.0003754149354888 | 0.0119107226198972 | 0.00892098657765581 | AP1M1/AP2B1/EPS15L1 | 3 |
| GO | B_12_9 | GO:0005774 | vacuolar membrane | 7/55 | 491/19960 | 0.00038175393012491 | 0.0119107226198972 | 0.00892098657765581 | AP1M1/AP2B1/CALCOCO2/RAB14/RMC1/SLC44A2/VPS39 | 7 |
| GO | B_12_9 | GO:0030132 | clathrin coat of coated pit | 2/55 | 18/19960 | 0.00110879903925057 | 0.0236158686262028 | 0.0176879987686135 | AP2B1/EPS15L1 | 2 |
| GO | B_12_9 | GO:0005769 | early endosome | 6/55 | 438/19960 | 0.00126042517668563 | 0.0236158686262028 | 0.0176879987686135 | AP1M1/RAB14/RABEP2/SNX1/TRAK2/WASHC2A | 6 |
| GO | B_12_9 | GO:0005765 | lysosomal membrane | 6/55 | 447/19960 | 0.00139831297365982 | 0.0236158686262028 | 0.0176879987686135 | AP1M1/AP2B1/RAB14/RMC1/SLC44A2/VPS39 | 6 |
| GO | B_12_9 | GO:0098852 | lytic vacuole membrane | 6/55 | 447/19960 | 0.00139831297365982 | 0.0236158686262028 | 0.0176879987686135 | AP1M1/AP2B1/RAB14/RMC1/SLC44A2/VPS39 | 6 |