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Selected Module: B_12_7
Module Info
| Module_Name | B_12_7 |
| Cell_Type | B |
| Name | B_12_7: RNA splicing |
| Meta_Module | B_6 |
| Gene_Number | 42 |
Genes:
AMD1, ATG12, ATP2B1, BAG5, BTG3, CCDC59, CCNT1, CLK1, CYLD, DNAJA1, DNTTIP2, DUSP10, DYNLL2, EIF5, FAM76B, G3BP2, GOLGA8B, HMGCS1, HNRNPH3, IDI1, ILF3, IVNS1ABP, MYLIP, NAF1, NECAP1, NFKBIZ, POLR2A, PPP1R15B, PTP4A1, RBMX, RIOK1, RSRC2, SLC25A36, SMNDC1, SRSF10, TMEM167B, TOPORS, TRA2B, TSPYL2, USP36, WDR45B, ZNF394
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| GCCATNTTG | 5.25192383417989e-06 | EIF5/HNRNPH3/ILF3/POLR2A/PPP1R15B/RBMX/RSRC2/TRA2B/TSPYL2 |
| NFMUE1 | 0.0043345724876704 | CLK1/EIF5/HNRNPH3/PPP1R15B/TRA2B |
| YY1 | 0.0043345724876704 | EIF5/HNRNPH3/POLR2A/PPP1R15B/TRA2B |
| HSF1 | 0.00510214321937256 | CYLD/DNAJA1/EIF5/NECAP1/RSRC2 |
| CREB3L2 | 0.00556491330840417 | CCDC59/HMGCS1/RIOK1/ZNF394 |
| PSMB5 | 0.00587931630723289 | DNAJA1/NFKBIZ/POLR2A/PPP1R15B/RBMX |
| SRPK1 | 0.00992879942092058 | CCNT1/DNTTIP2/EIF5/HNRNPH3/SRSF10 |
| SMTTTTGT | 0.00992879942092058 | CLK1/ILF3/PTP4A1/RBMX/TRA2B |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_12_7 | D015694 | Gene Products, rev | 3/42 | 136/26076 | 0.0013727935385117 | 0.0454077862738487 | 0.0396831816395691 | CCNT1/ILF3/POLR2A | 3 |
| MeSH_gene2pubmed | B_12_7 | D022003 | Cell Nucleus Structures | 3/42 | 136/26076 | 0.0013727935385117 | 0.0454077862738487 | 0.0396831816395691 | CCNT1/TOPORS/TRA2B | 3 |
| GO | B_12_7 | GO:0009251 | glucan catabolic process | 2/39 | 27/18986 | 0.00139706184327509 | 0.0388942017167786 | 0.0300588885016241 | ATG12/WDR45B | 2 |
| GO | B_12_7 | GO:0033119 | negative regulation of RNA splicing | 2/39 | 27/18986 | 0.00139706184327509 | 0.0388942017167786 | 0.0300588885016241 | RBMX/SRSF10 | 2 |
| GO | B_12_7 | GO:0042026 | protein refolding | 2/39 | 27/18986 | 0.00139706184327509 | 0.0388942017167786 | 0.0300588885016241 | BAG5/DNAJA1 | 2 |
| KEGG | B_12_7 | hsa00900 | Terpenoid backbone biosynthesis | 2/21 | 23/8541 | 0.00141213999471044 | 0.0362569677892839 | 0.0354391414481723 | HMGCS1/IDI1 | 2 |
| GO | B_12_7 | GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway | 3/39 | 112/18986 | 0.00156466328022255 | 0.0391573404654642 | 0.0302622519326258 | BAG5/DNAJA1/IVNS1ABP | 3 |
| GO | B_12_7 | GO:0000272 | polysaccharide catabolic process | 2/39 | 29/18986 | 0.00161179125684605 | 0.0391573404654642 | 0.0302622519326258 | ATG12/WDR45B | 2 |
| GO | B_12_7 | GO:0008299 | isoprenoid biosynthetic process | 2/39 | 29/18986 | 0.00161179125684605 | 0.0391573404654642 | 0.0302622519326258 | HMGCS1/IDI1 | 2 |
| GO | B_12_7 | GO:0048024 | regulation of mRNA splicing, via spliceosome | 3/39 | 114/18986 | 0.00164611331449742 | 0.0391573404654642 | 0.0302622519326258 | RBMX/SRSF10/TRA2B | 3 |