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Selected Module: B_12_7
Module Info
| Module_Name | B_12_7 |
| Cell_Type | B |
| Name | B_12_7: RNA splicing |
| Meta_Module | B_6 |
| Gene_Number | 42 |
Genes:
AMD1, ATG12, ATP2B1, BAG5, BTG3, CCDC59, CCNT1, CLK1, CYLD, DNAJA1, DNTTIP2, DUSP10, DYNLL2, EIF5, FAM76B, G3BP2, GOLGA8B, HMGCS1, HNRNPH3, IDI1, ILF3, IVNS1ABP, MYLIP, NAF1, NECAP1, NFKBIZ, POLR2A, PPP1R15B, PTP4A1, RBMX, RIOK1, RSRC2, SLC25A36, SMNDC1, SRSF10, TMEM167B, TOPORS, TRA2B, TSPYL2, USP36, WDR45B, ZNF394
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| GCCATNTTG | 5.25192383417989e-06 | EIF5/HNRNPH3/ILF3/POLR2A/PPP1R15B/RBMX/RSRC2/TRA2B/TSPYL2 |
| NFMUE1 | 0.0043345724876704 | CLK1/EIF5/HNRNPH3/PPP1R15B/TRA2B |
| YY1 | 0.0043345724876704 | EIF5/HNRNPH3/POLR2A/PPP1R15B/TRA2B |
| HSF1 | 0.00510214321937256 | CYLD/DNAJA1/EIF5/NECAP1/RSRC2 |
| CREB3L2 | 0.00556491330840417 | CCDC59/HMGCS1/RIOK1/ZNF394 |
| PSMB5 | 0.00587931630723289 | DNAJA1/NFKBIZ/POLR2A/PPP1R15B/RBMX |
| SRPK1 | 0.00992879942092058 | CCNT1/DNTTIP2/EIF5/HNRNPH3/SRSF10 |
| SMTTTTGT | 0.00992879942092058 | CLK1/ILF3/PTP4A1/RBMX/TRA2B |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_12_7 | GO:1903321 | negative regulation of protein modification by small protein conjugation or removal | 3/39 | 94/18986 | 0.00094395523276047 | 0.0352257810676974 | 0.0272237963181993 | BAG5/DNAJA1/IVNS1ABP | 3 |
| MeSH_gene2pubmed | B_12_7 | D020541 | Coiled Bodies | 3/42 | 120/26076 | 0.0009571788589544 | 0.0391987532714662 | 0.0342569275836315 | NAF1/TOPORS/TSPYL2 | 3 |
| GO | B_12_7 | GO:0044804 | nucleophagy | 2/39 | 23/18986 | 0.00101223508815222 | 0.0352257810676974 | 0.0272237963181993 | ATG12/WDR45B | 2 |
| GO | B_12_7 | GO:0050686 | negative regulation of mRNA processing | 2/39 | 23/18986 | 0.00101223508815222 | 0.0352257810676974 | 0.0272237963181993 | RBMX/SRSF10 | 2 |
| GO | B_12_7 | GO:1901874 | negative regulation of post-translational protein modification | 3/39 | 98/18986 | 0.00106502990618274 | 0.035298134033485 | 0.027279713386435 | BAG5/DNAJA1/IVNS1ABP | 3 |
| MeSH_gene2pubmed | B_12_7 | D015684 | Gene Products, pol | 2/42 | 30/26076 | 0.001070608871082 | 0.0418510740513874 | 0.0365748676532321 | CCNT1/ILF3 | 2 |
| MeSH_gene2pubmed | B_12_7 | D017411 | Ribonucleoproteins, Small Nuclear | 5/42 | 492/26076 | 0.00112095465517565 | 0.0419139566717852 | 0.0366298225993325 | CCNT1/NAF1/POLR2A/RBMX/SMNDC1 | 5 |
| hallmark | B_12_7 | HALLMARK_G2M_CHECKPOINT | HALLMARK_G2M_CHECKPOINT | 5/19 | 200/4384 | 0.00129399886021353 | 0.0271739760644842 | 0.0231557690775053 | AMD1/CCNT1/ILF3/SRSF10/TRA2B | 5 |
| GO | B_12_7 | GO:0005980 | glycogen catabolic process | 2/39 | 26/18986 | 0.00129525374913932 | 0.0388942017167786 | 0.0300588885016241 | ATG12/WDR45B | 2 |
| MeSH_gene2pubmed | B_12_7 | D010457 | Peptidoglycan | 3/42 | 134/26076 | 0.00131561006302601 | 0.0454077862738487 | 0.0396831816395691 | CCNT1/CYLD/NFKBIZ | 3 |