Module Explorer
Instructions
- Enter a module name.
- Click Submit to search for the detailed information of the module.
- Results will appear below if available.
Selected Module: B_12_7
Module Info
| Module_Name | B_12_7 |
| Cell_Type | B |
| Name | B_12_7: RNA splicing |
| Meta_Module | B_6 |
| Gene_Number | 42 |
Genes:
AMD1, ATG12, ATP2B1, BAG5, BTG3, CCDC59, CCNT1, CLK1, CYLD, DNAJA1, DNTTIP2, DUSP10, DYNLL2, EIF5, FAM76B, G3BP2, GOLGA8B, HMGCS1, HNRNPH3, IDI1, ILF3, IVNS1ABP, MYLIP, NAF1, NECAP1, NFKBIZ, POLR2A, PPP1R15B, PTP4A1, RBMX, RIOK1, RSRC2, SLC25A36, SMNDC1, SRSF10, TMEM167B, TOPORS, TRA2B, TSPYL2, USP36, WDR45B, ZNF394
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| GCCATNTTG | 5.25192383417989e-06 | EIF5/HNRNPH3/ILF3/POLR2A/PPP1R15B/RBMX/RSRC2/TRA2B/TSPYL2 |
| NFMUE1 | 0.0043345724876704 | CLK1/EIF5/HNRNPH3/PPP1R15B/TRA2B |
| YY1 | 0.0043345724876704 | EIF5/HNRNPH3/POLR2A/PPP1R15B/TRA2B |
| HSF1 | 0.00510214321937256 | CYLD/DNAJA1/EIF5/NECAP1/RSRC2 |
| CREB3L2 | 0.00556491330840417 | CCDC59/HMGCS1/RIOK1/ZNF394 |
| PSMB5 | 0.00587931630723289 | DNAJA1/NFKBIZ/POLR2A/PPP1R15B/RBMX |
| SRPK1 | 0.00992879942092058 | CCNT1/DNTTIP2/EIF5/HNRNPH3/SRSF10 |
| SMTTTTGT | 0.00992879942092058 | CLK1/ILF3/PTP4A1/RBMX/TRA2B |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_12_7 | GO:0031397 | negative regulation of protein ubiquitination | 3/39 | 81/18986 | 0.00061200332998875 | 0.0278947858580868 | 0.0215581300264403 | BAG5/DNAJA1/IVNS1ABP | 3 |
| MeSH_gene2pubmed | B_12_7 | D029543 | Nucleocytoplasmic Transport Proteins | 4/42 | 243/26076 | 0.00062358646277444 | 0.0315461387050604 | 0.0275690857226599 | ILF3/RBMX/SRSF10/TRA2B | 4 |
| GO | B_12_7 | GO:0031400 | negative regulation of protein modification process | 5/39 | 342/18986 | 0.00064125944501348 | 0.0278947858580868 | 0.0215581300264403 | BAG5/DNAJA1/DUSP10/IVNS1ABP/PPP1R15B | 5 |
| WikiPathways | B_12_7 | WP5304 | Cholesterol metabolism | 3/22 | 72/8836 | 0.00071488818620772 | 0.00631484564483491 | 0.00438966430127551 | HMGCS1/IDI1/MYLIP | 3 |
| MeSH_gene2pubmed | B_12_7 | D018869 | Heat-Shock Response | 4/42 | 254/26076 | 0.00073574532534639 | 0.0351522766554391 | 0.0307205942863935 | CCNT1/DNAJA1/SRSF10/TRA2B | 4 |
| GO | B_12_7 | GO:0034045 | phagophore assembly site membrane | 2/41 | 21/19960 | 0.00084337236604317 | 0.0289557845674822 | 0.0245613706602047 | ATG12/WDR45B | 2 |
| MeSH_gene2pubmed | B_12_7 | D034802 | RNA-Binding Protein EWS | 3/42 | 116/26076 | 0.00086772733023475 | 0.0391987532714662 | 0.0342569275836315 | CCNT1/POLR2A/SRSF10 | 3 |
| WikiPathways | B_12_7 | WP5193 | Cholesterol synthesis disorders | 2/22 | 18/8836 | 0.00088386032084897 | 0.00669208528642794 | 0.00465189642552091 | HMGCS1/IDI1 | 2 |
| GO | B_12_7 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome | 2/39 | 22/18986 | 0.00092541409566126 | 0.0352257810676974 | 0.0272237963181993 | RBMX/SRSF10 | 2 |
| MeSH_gene2pubmed | B_12_7 | D054321 | rev Gene Products, Human Immunodeficiency Virus | 3/42 | 119/26076 | 0.0009342919499827 | 0.0391987532714662 | 0.0342569275836315 | CCNT1/ILF3/POLR2A | 3 |