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Selected Module: B_12_7
Module Info
| Module_Name | B_12_7 |
| Cell_Type | B |
| Name | B_12_7: RNA splicing |
| Meta_Module | B_6 |
| Gene_Number | 42 |
Genes:
AMD1, ATG12, ATP2B1, BAG5, BTG3, CCDC59, CCNT1, CLK1, CYLD, DNAJA1, DNTTIP2, DUSP10, DYNLL2, EIF5, FAM76B, G3BP2, GOLGA8B, HMGCS1, HNRNPH3, IDI1, ILF3, IVNS1ABP, MYLIP, NAF1, NECAP1, NFKBIZ, POLR2A, PPP1R15B, PTP4A1, RBMX, RIOK1, RSRC2, SLC25A36, SMNDC1, SRSF10, TMEM167B, TOPORS, TRA2B, TSPYL2, USP36, WDR45B, ZNF394
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| GCCATNTTG | 5.25192383417989e-06 | EIF5/HNRNPH3/ILF3/POLR2A/PPP1R15B/RBMX/RSRC2/TRA2B/TSPYL2 |
| NFMUE1 | 0.0043345724876704 | CLK1/EIF5/HNRNPH3/PPP1R15B/TRA2B |
| YY1 | 0.0043345724876704 | EIF5/HNRNPH3/POLR2A/PPP1R15B/TRA2B |
| HSF1 | 0.00510214321937256 | CYLD/DNAJA1/EIF5/NECAP1/RSRC2 |
| CREB3L2 | 0.00556491330840417 | CCDC59/HMGCS1/RIOK1/ZNF394 |
| PSMB5 | 0.00587931630723289 | DNAJA1/NFKBIZ/POLR2A/PPP1R15B/RBMX |
| SRPK1 | 0.00992879942092058 | CCNT1/DNTTIP2/EIF5/HNRNPH3/SRSF10 |
| SMTTTTGT | 0.00992879942092058 | CLK1/ILF3/PTP4A1/RBMX/TRA2B |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_12_7 | GO:0008380 | RNA splicing | 9/39 | 484/18986 | 4.53084671283784e-07 | 0.00031534693121351 | 0.00024371186002738 | CLK1/HNRNPH3/ILF3/IVNS1ABP/POLR2A/RBMX/SMNDC1/SRSF10/TRA2B | 9 |
| GO | B_12_7 | GO:0043484 | regulation of RNA splicing | 6/39 | 190/18986 | 2.30077922341171e-06 | 0.00080067116974727 | 0.00061878851745441 | CLK1/HNRNPH3/POLR2A/RBMX/SRSF10/TRA2B | 6 |
| MeSH_gene2pubmed | B_12_7 | D020365 | RNA Helicases | 7/42 | 447/26076 | 6.66785713642815e-06 | 0.00299492460983604 | 0.00261735149500971 | ATG12/ILF3/POLR2A/RBMX/SMNDC1/SRSF10/TRA2B | 7 |
| MeSH_gene2pubmed | B_12_7 | D034441 | Heterogeneous-Nuclear Ribonucleoproteins | 7/42 | 450/26076 | 6.96494095310708e-06 | 0.00299492460983604 | 0.00261735149500971 | CCNT1/HNRNPH3/IVNS1ABP/POLR2A/RBMX/SRSF10/TRA2B | 7 |
| WikiPathways | B_12_7 | WP411 | mRNA processing | 5/22 | 140/8836 | 1.97044741507239e-05 | 0.00104433712998836 | 0.00072595431081614 | CLK1/POLR2A/RBMX/SRSF10/TRA2B | 5 |
| MeSH_gene2pubmed | B_12_7 | D002247 | Carbon Isotopes | 5/42 | 221/26076 | 2.75365668542196e-05 | 0.00619926329359038 | 0.00541771602401901 | G3BP2/ILF3/PTP4A1/RBMX/TRA2B | 5 |
| MeSH_gene2pubmed | B_12_7 | D034541 | Heterogeneous-Nuclear Ribonucleoprotein Group F-H | 3/42 | 42/26076 | 4.26939356042834e-05 | 0.00619926329359038 | 0.00541771602401901 | HNRNPH3/ILF3/POLR2A | 3 |
| MeSH_gene2pubmed | B_12_7 | D036961 | Matrix Attachment Region Binding Proteins | 4/42 | 121/26076 | 4.30780424653277e-05 | 0.00619926329359038 | 0.00541771602401901 | POLR2A/RBMX/SRSF10/TRA2B | 4 |
| MeSH_gene2pubmed | B_12_7 | D055532 | SMN Complex Proteins | 4/42 | 124/26076 | 4.740405665523e-05 | 0.00619926329359038 | 0.00541771602401901 | POLR2A/RBMX/SMNDC1/TRA2B | 4 |
| GO | B_12_7 | GO:0046329 | negative regulation of JNK cascade | 3/39 | 35/18986 | 5.01144999147391e-05 | 0.0112392729631213 | 0.00868612898390043 | CYLD/DNAJA1/DUSP10 | 3 |