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Selected Module: B_12_6
Module Info
| Module_Name | B_12_6 |
| Cell_Type | B |
| Name | B_12_6: RNA polymerase II-specific DNA-binding transcription factor binding |
| Meta_Module | B_6 |
| Gene_Number | 31 |
Genes:
AKAP8, ARL6IP1, BIRC2, C11orf58, CHD4, CSDE1, CTNNB1, DBF4, DDX24, DHX9, EZR, FUBP1, GTPBP4, MALAT1, MED13, MEF2D, NUP54, OTUD4, PPP2R3C, PRPF40A, RAB22A, SLC25A33, SPPL2A, TAB2, TAMALIN, TCERG1, TP53BP2, UBQLN1, USP16, ZBTB21, ZNF326
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| CCAWNWWNNNGGC | 0.00075078075391258 | CSDE1/MED13/RAB22A/ZNF326 |
| AAGWWRNYGGC | 0.0494759839291753 | CHD4/RAB22A/ZNF326 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_12_6 | GO:0031593 | polyubiquitin modification-dependent protein binding | 2/31 | 58/18737 | 0.0041336230165678 | 0.0258401445724203 | 0.0146462357900358 | TAB2/UBQLN1 | 2 |
| GO | B_12_6 | GO:0061980 | regulatory RNA binding | 2/31 | 58/18737 | 0.0041336230165678 | 0.0258401445724203 | 0.0146462357900358 | DHX9/MALAT1 | 2 |
| GO | B_12_6 | GO:0001098 | basal transcription machinery binding | 2/31 | 60/18737 | 0.00441711873032826 | 0.0258401445724203 | 0.0146462357900358 | DHX9/ZNF326 | 2 |
| GO | B_12_6 | GO:0001099 | basal RNA polymerase II transcription machinery binding | 2/31 | 60/18737 | 0.00441711873032826 | 0.0258401445724203 | 0.0146462357900358 | DHX9/ZNF326 | 2 |
| GO | B_12_6 | GO:0003724 | RNA helicase activity | 2/31 | 77/18737 | 0.00717567971427443 | 0.039978786979529 | 0.0226600412029719 | DDX24/DHX9 | 2 |
| GO | B_12_6 | GO:0008186 | ATP-dependent activity, acting on RNA | 2/31 | 79/18737 | 0.007540320201032 | 0.0401007937963975 | 0.0227291948643548 | DDX24/DHX9 | 2 |