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Selected Module: B_12_6


Module Info

Module_Name B_12_6
Cell_Type B
Name B_12_6: RNA polymerase II-specific DNA-binding transcription factor binding
Meta_Module B_6
Gene_Number 31

Genes:

AKAP8, ARL6IP1, BIRC2, C11orf58, CHD4, CSDE1, CTNNB1, DBF4, DDX24, DHX9, EZR, FUBP1, GTPBP4, MALAT1, MED13, MEF2D, NUP54, OTUD4, PPP2R3C, PRPF40A, RAB22A, SLC25A33, SPPL2A, TAB2, TAMALIN, TCERG1, TP53BP2, UBQLN1, USP16, ZBTB21, ZNF326


UMAP Visualizations


UMAP for B_12_6

UMAP for B_12_6


Word Cloud

Enriched TF

Wordcloud for B_12_6
TF p.adjust Genes
CCAWNWWNNNGGC 0.00075078075391258 CSDE1/MED13/RAB22A/ZNF326
AAGWWRNYGGC 0.0494759839291753 CHD4/RAB22A/ZNF326


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_12_6 GO:0051059 NF-kappaB binding 2/31 31/18737 0.00119556116263899 0.0118666132448557 0.00672601560437168 AKAP8/TP53BP2 2
GO B_12_6 GO:0042826 histone deacetylase binding 3/31 128/18737 0.00121708853793392 0.0118666132448557 0.00672601560437168 AKAP8/CHD4/MEF2D 3
reactome B_12_6 R-HSA-168638 NOD1/2 Signaling Pathway 2/17 37/11146 0.00141321603927959 0.0474787647197263 0.0315974380257421 BIRC2/TAB2 2
reactome B_12_6 R-HSA-111465 Apoptotic cleavage of cellular proteins 2/17 38/11146 0.00149039159373204 0.0474787647197263 0.0315974380257421 BIRC2/CTNNB1 2
reactome B_12_6 R-HSA-73887 Death Receptor Signaling 3/17 154/11146 0.00152568756154937 0.0474787647197263 0.0315974380257421 BIRC2/SPPL2A/TAB2 3
reactome B_12_6 R-HSA-9031628 NGF-stimulated transcription 2/17 39/11146 0.00156954594114798 0.0474787647197263 0.0315974380257421 CHD4/MEF2D 2
GO B_12_6 GO:0000993 RNA polymerase II complex binding 2/31 36/18737 0.00161147533667965 0.0145032780301168 0.00822048147456014 DHX9/ZNF326 2
GO B_12_6 GO:0004386 helicase activity 3/31 154/18737 0.0020672301156008 0.0170725869087883 0.0096767699078152 CHD4/DDX24/DHX9 3
GO B_12_6 GO:0043175 RNA polymerase core enzyme binding 2/31 42/18737 0.00218879319343439 0.0170725869087883 0.0096767699078152 DHX9/ZNF326 2
GO B_12_6 GO:0051018 protein kinase A binding 2/31 53/18737 0.00346368562278838 0.02532820111664 0.0143560654102413 AKAP8/EZR 2