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Selected Module: B_12_6
Module Info
| Module_Name | B_12_6 |
| Cell_Type | B |
| Name | B_12_6: RNA polymerase II-specific DNA-binding transcription factor binding |
| Meta_Module | B_6 |
| Gene_Number | 31 |
Genes:
AKAP8, ARL6IP1, BIRC2, C11orf58, CHD4, CSDE1, CTNNB1, DBF4, DDX24, DHX9, EZR, FUBP1, GTPBP4, MALAT1, MED13, MEF2D, NUP54, OTUD4, PPP2R3C, PRPF40A, RAB22A, SLC25A33, SPPL2A, TAB2, TAMALIN, TCERG1, TP53BP2, UBQLN1, USP16, ZBTB21, ZNF326
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| CCAWNWWNNNGGC | 0.00075078075391258 | CSDE1/MED13/RAB22A/ZNF326 |
| AAGWWRNYGGC | 0.0494759839291753 | CHD4/RAB22A/ZNF326 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_12_6 | GO:2000767 | positive regulation of cytoplasmic translation | 2/31 | 16/18986 | 0.00030523090629008 | 0.0491443848493514 | 0.0365247210316733 | CSDE1/DHX9 | 2 |
| GO | B_12_6 | GO:0031396 | regulation of protein ubiquitination | 4/31 | 205/18986 | 0.00033046176171513 | 0.0491443848493514 | 0.0365247210316733 | BIRC2/CTNNB1/GTPBP4/UBQLN1 | 4 |
| GO | B_12_6 | GO:0035613 | RNA stem-loop binding | 2/31 | 21/18737 | 0.00054552247246436 | 0.00994202270383551 | 0.00563515456897559 | CSDE1/DHX9 | 2 |
| GO | B_12_6 | GO:0043130 | ubiquitin binding | 3/31 | 100/18737 | 0.00059482187116964 | 0.00994202270383551 | 0.00563515456897559 | BIRC2/TAB2/USP16 | 3 |
| reactome | B_12_6 | R-HSA-72203 | Processing of Capped Intron-Containing Pre-mRNA | 4/17 | 285/11146 | 0.00076562453745859 | 0.0474787647197263 | 0.0315974380257421 | DHX9/NUP54/PRPF40A/TCERG1 | 4 |
| GO | B_12_6 | GO:0034237 | protein kinase A regulatory subunit binding | 2/31 | 25/18737 | 0.00077611185643509 | 0.0113506359003633 | 0.0064335588099225 | AKAP8/EZR | 2 |
| reactome | B_12_6 | R-HSA-525793 | Myogenesis | 2/17 | 30/11146 | 0.00092885713749704 | 0.0474787647197263 | 0.0315974380257421 | CTNNB1/MEF2D | 2 |
| GO | B_12_6 | GO:0097718 | disordered domain specific binding | 2/31 | 28/18737 | 0.00097488316804663 | 0.0118199279678703 | 0.00669955431377264 | CTNNB1/EZR | 2 |
| GO | B_12_6 | GO:0032182 | ubiquitin-like protein binding | 3/31 | 120/18737 | 0.00101025025366413 | 0.0118199279678703 | 0.00669955431377264 | BIRC2/TAB2/USP16 | 3 |
| reactome | B_12_6 | R-HSA-5357956 | TNFR1-induced NF-kappa-B signaling pathway | 2/17 | 33/11146 | 0.00112441201589804 | 0.0474787647197263 | 0.0315974380257421 | BIRC2/TAB2 | 2 |