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Selected Module: B_12_19
Module Info
| Module_Name | B_12_19 |
| Cell_Type | B |
| Name | B_12_19: mitochondrial cytochrome c oxidase assembly |
| Meta_Module | B_18 |
| Gene_Number | 26 |
Genes:
AAAS, AGK, ALDH18A1, COMMD1, COPZ1, COQ5, COX16, DNTTIP1, DRG1, FIS1, HMG20B, IDH3G, LONP1, MTG2, PDZD11, PIGF, POLR3H, RSU1, SEC61G, SELENOT, STX18, SURF1, TACO1, TKFC, UBE2M, UQCR11
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| GABP | 0.00787219954965325 | DNTTIP1/IDH3G/PDZD11/PIGF |
| RORA | 0.00787219954965325 | ALDH18A1/COX16/STX18/TACO1 |
| ALKBH3 | 0.0334911722468617 | AGK/COX16/STX18/TACO1 |
| WDHD1 | 0.0334911722468617 | AAAS/COX16/STX18 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_12_19 | R-HSA-611105 | Respiratory electron transport | 4/23 | 158/11146 | 0.00027896003590208 | 0.0127391749728619 | 0.0115499242934898 | COX16/SURF1/TACO1/UQCR11 | 4 |
| GO | B_12_19 | GO:0033108 | mitochondrial respiratory chain complex assembly | 3/25 | 103/18986 | 0.00032697944254475 | 0.0244580623023474 | 0.0191369021110402 | COX16/SURF1/TACO1 | 3 |
| GO | B_12_19 | GO:0097250 | mitochondrial respirasome assembly | 3/25 | 114/18986 | 0.00044036844934106 | 0.0274496333422595 | 0.0214776191082132 | COX16/SURF1/TACO1 | 3 |
| GO | B_12_19 | GO:0070129 | regulation of mitochondrial translation | 2/25 | 26/18986 | 0.00053060877822715 | 0.0283496690081364 | 0.0221818406537065 | MTG2/TACO1 | 2 |
| GO | B_12_19 | GO:0062125 | regulation of mitochondrial gene expression | 2/25 | 34/18986 | 0.00091002087472995 | 0.0425434758936256 | 0.0332876056809116 | MTG2/TACO1 | 2 |
| hallmark | B_12_19 | HALLMARK_ADIPOGENESIS | HALLMARK_ADIPOGENESIS | 3/10 | 200/4384 | 0.00884735282973937 | 0.0353894113189575 | 0.0232825074466825 | COQ5/IDH3G/UQCR11 | 3 |
| hallmark | B_12_19 | HALLMARK_OXIDATIVE_PHOSPHORYLATION | HALLMARK_OXIDATIVE_PHOSPHORYLATION | 3/10 | 200/4384 | 0.00884735282973937 | 0.0353894113189575 | 0.0232825074466825 | IDH3G/SURF1/UQCR11 | 3 |