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Selected Module: B_12_19


Module Info

Module_Name B_12_19
Cell_Type B
Name B_12_19: mitochondrial cytochrome c oxidase assembly
Meta_Module B_18
Gene_Number 26

Genes:

AAAS, AGK, ALDH18A1, COMMD1, COPZ1, COQ5, COX16, DNTTIP1, DRG1, FIS1, HMG20B, IDH3G, LONP1, MTG2, PDZD11, PIGF, POLR3H, RSU1, SEC61G, SELENOT, STX18, SURF1, TACO1, TKFC, UBE2M, UQCR11


UMAP Visualizations


UMAP for B_12_19

UMAP for B_12_19


Word Cloud

Enriched TF

Wordcloud for B_12_19
TF p.adjust Genes
GABP 0.00787219954965325 DNTTIP1/IDH3G/PDZD11/PIGF
RORA 0.00787219954965325 ALDH18A1/COX16/STX18/TACO1
ALKBH3 0.0334911722468617 AGK/COX16/STX18/TACO1
WDHD1 0.0334911722468617 AAAS/COX16/STX18


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_12_19 GO:0033617 mitochondrial cytochrome c oxidase assembly 3/25 25/18986 4.55059476622323e-06 0.00134722594634479 0.00105411993550197 COX16/SURF1/TACO1 3
GO B_12_19 GO:0008535 respiratory chain complex IV assembly 3/25 29/18986 7.20441682537319e-06 0.00134722594634479 0.00105411993550197 COX16/SURF1/TACO1 3
GO B_12_19 GO:0017004 cytochrome complex assembly 3/25 41/18986 2.07997432571673e-05 0.00198533796438322 0.00155340262904176 COX16/SURF1/TACO1 3
GO B_12_19 GO:0007005 mitochondrion organization 6/25 452/18986 2.12335611163981e-05 0.00198533796438322 0.00155340262904176 AGK/COX16/FIS1/LONP1/SURF1/TACO1 6
WikiPathways B_12_19 WP4922 Mitochondrial complex IV assembly 3/16 34/8836 2.81733505974708e-05 0.00073250711553424 0.0005041546949021 COX16/SURF1/TACO1 3
reactome B_12_19 R-HSA-9864848 Complex IV assembly 3/23 48/11146 0.00012495699023901 0.0108545861607828 0.00984126905088256 COX16/SURF1/TACO1 3
MeSH_gene2pubmed B_12_19 D049069 ATP-Dependent Proteases 2/26 18/26076 0.00014483573694859 0.0378006691446609 0.032375210484445 FIS1/LONP1 2
reactome B_12_19 R-HSA-1428517 Aerobic respiration and respiratory electron transport 5/23 260/11146 0.00015846111183624 0.0108545861607828 0.00984126905088256 COX16/IDH3G/SURF1/TACO1/UQCR11 5
WikiPathways B_12_19 WP5504 Disorders of Mitochondrial Homeostatis Dynamics Protein Import and Quality Control 3/16 63/8836 0.00018106643083297 0.00235386360082863 0.00162006806534764 AGK/COQ5/LONP1 3
MeSH_gene2pubmed B_12_19 D007706 Menkes Kinky Hair Syndrome 2/26 21/26076 0.00019842870942079 0.0378006691446609 0.032375210484445 COMMD1/PDZD11 2